A Multi-centre Survey of Epidemiology, Treatment and Outcome of Patients Suffering an Out-of-hospital Cardiac Arrest

NCT02236819 | Completed

• 2 other identifiers: eureca1-2014eureca 2014
• Study Type: observational
• Target: 10,682
• Locations: 1 country
• Sites: 1

Brief Summary

There is considerable variation in the incidence of out-of-hospital cardiac arrest (OHCA) across Europe. The likelihood of attempted resuscitation also varies. To better understand the factors that contribute to variation, more data on incidence, management and outcomes from OHCA is required. A European, multi-centre study provides the opportunity to uncover differences throughout Europe and may help find explanations for these differences. Results may also have potential to support the development of quality benchmarking between European Emergency Medical Services (EMS). This prospective European study will involve 27 different countries. It provides a common Utstein-based dataset, data collection methodology and a common data collection period for all participants, thereby potentially increasing comparability. Study research questions will address the following: OHCA incidence in different European regions; incidence of cardiopulmonary resuscitation (CPR) attempted; initial presenting rhythm in patients where bystanders or EMS starts CPR or any other resuscitation intervention; rate of any return of spontaneous circulation (ROSC); patient status at handover to a hospital i.e. ROSC, ongoing CPR, dead; incidence of patients still alive 30 days after OHCA; incidence of patients discharged alive from hospital.

Conditions

Out of Hospital Cardiac Arrest

Outcome Measures

Primary Outcomes (1)

• incidence of patients still alive 30 days after out of hospital cardiac arrest or patients discharged alive from hospital

  co primary outcome is ROSC/admission to hospital in cases, victims have no ROSC or died on scene

  30 days after OHCA

Secondary Outcomes (2)

• patient status at handover to a hospital

  Hospital admission after EMS treatment (within first 24h after OHCA)

• return of spontaneous circulation

  during the time period of EMS treatment within the first 24 h after OHCA

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Residents of 27 European countries

You may qualify if:

• All patients who suffer an out of hospital cardiac arrest and are attended by the EMS at any stage during the event.

Sponsors & Collaborators

• German Resuscitation Registry: lead
• European Resuscitation Council (ERC): collaborator

Study Sites (1)

Germany ans 26 other european registries

Kiel, Germany

Location

Related Publications (2)

• Grasner JT, Bottiger BW, Bossaert L; European Registry of Cardiac Arrest (EuReCa) ONE Steering Committee; EuReCa ONE Study Management Team. EuReCa ONE - ONE month - ONE Europe - ONE goal. Resuscitation. 2014 Oct;85(10):1307-8. doi: 10.1016/j.resuscitation.2014.08.001. Epub 2014 Aug 15. No abstract available.

  PMID: 25132474 BACKGROUND

• Wnent J, Masterson S, Grasner JT, Bottiger BW, Herlitz J, Koster RW, Rosell Ortiz F, Tjelmeland I, Maurer H, Bossaert L. EuReCa ONE - 27 Nations, ONE Europe, ONE Registry: a prospective observational analysis over one month in 27 resuscitation registries in Europe - the EuReCa ONE study protocol. Scand J Trauma Resusc Emerg Med. 2015 Jan 24;23:7. doi: 10.1186/s13049-015-0093-3.

  PMID: 25927980 DERIVED

Related Links

• Official study website

MeSH Terms

Conditions

Out-of-Hospital Cardiac Arrest

Condition Hierarchy (Ancestors)

Heart Arrest; Heart Diseases; Cardiovascular Diseases

Study Officials

• Jan-Thorsten Gräsner, MD

  German Resuscitation Registry

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 30 Days
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Medical Director Emergency Medicine University Hospital Schleswig-Holstein, Campus Kiel, Germany

Study Record Dates

• First Submitted: September 2, 2014
• First Posted: September 11, 2014
• Study Start: October 1, 2014
• Primary Completion: December 1, 2014
• Study Completion: December 1, 2014
• Last Updated: June 19, 2018

Record last verified: 2018-06

Locations

DE (1)