NCT02213406

Brief Summary

This project will examine neuronal and sensory fat perception. Our hypothesis is that subjects being either hypersensitive or hyposensitive for fat will show different brain activities. Therefore the investigators will conduct functional magnetic resonance imaging (fMRI) and fat detection threshold tests examining neuronal and sensory fat perception.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 5, 2014

Completed
6 days until next milestone

First Posted

Study publicly available on registry

August 11, 2014

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2017

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2017

Completed
Last Updated

July 6, 2017

Status Verified

July 1, 2017

First QC Date

August 5, 2014

Last Update Submit

July 4, 2017

Conditions

Fat Perception in the Brain

Outcome Measures

Primary Outcomes (1)

  • Fat detection thresholds

    A sensory test will be conducted to establish individual fat detection thresholds. It is expected that subjects\* brain activity is dependent on sensory fat sensitivity.

    each measurement day

Secondary Outcomes (1)

  • Brain activity

    pre and post meal intake

Study Arms (1)

intervention group

EXPERIMENTAL

Fat detection threshold test, intake of high and low fat yogurt, fMRI-measurements

Dietary Supplement: yogurt

Interventions

yogurtDIETARY_SUPPLEMENT

Subjects will receive yogurt with varying fat concentrations

intervention group

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • healthy

You may not qualify if:

  • lactose intolerance
  • fMRI contraindications (metal implants,...)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Clinic of Tuebingen, fMEG Center

Tübingen, 72076, Germany

Location

MeSH Terms

Interventions

Yogurt

Intervention Hierarchy (Ancestors)

Cultured Milk ProductsMilkBeveragesDiet, Food, and NutritionPhysiological PhenomenaFermented FoodsDairy ProductsFoodFood and Beverages

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr.

Study Record Dates

First Submitted

August 5, 2014

First Posted

August 11, 2014

Primary Completion

June 1, 2017

Study Completion

July 1, 2017

Last Updated

July 6, 2017

Record last verified: 2017-07

Locations

DE(1)