Does Exercise Snacking Improve Muscle Function in Older Adults?

NCT02991989 | Completed

• 1 other identifier: UoB-ESS-01
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

Muscle size declines at around 0.5-1% per year after 50 years of age, with muscle strength declining up to twice as fast as muscle size. This may eventually lead to loss of independence if tasks of daily living become too strenuous to be performed safely. Exercise is recognized as a safe and effective means to counteract muscle loss during aging, however access to gym equipment may be logistically challenging or unpalatable to older adults. This research is designed to investigate the effect of 28 days of home-based leg exercise that doesn't require exercise equipment or supervision (exercise snacking), accompanied with a daily protein supplement in the form of commercially available yogurt, on the skeletal muscle health (i.e. function and size) of independent, community-dwelling older adults. To achieve this, two groups will be compared; one group will undertake exercise snacking and consume a 150 g yogurt with the breakfast meal for four weeks, with the second group only receiving the daily yogurt with no exercise snacking.

Conditions

Muscle Function

Keywords

Home-based exercise; Exercise snacking; Protein; Yogurt

Outcome Measures

Primary Outcomes (1)

• 60 second sit to stand test

  The participant is asked to stand up from sitting in a chair whilst keeping their arms folded across their chest, then return to the seated position as many times as possible in a minute.

  28 days- change from pre- to post- intervention period

Secondary Outcomes (12)

• Lower limb muscle power

  28 days- change from pre- to post- intervention period

• Lower limb movement outcome variability

  28 days- change from pre- to post- intervention period

• Lower limb muscle cross-sectional area

  28 days- change from pre- to post- intervention period

• Lower limb muscle cross-sectional tissue density

  28 days- change from pre- to post- intervention period

• Body composition

  28 days- change from pre- to post- intervention period

Study Arms (2)

Exercise Snacking Group

EXPERIMENTAL

For 28 days, this group will be asked to perform two 'exercise snacks' a day; once in the morning and once in the evening. They will also be asked to consume 150 g of yogurt with the breakfast meal. The yogurt will be provided by the researchers.

Behavioral: Exercise Snacking; Dietary Supplement: Yogurt

Yogurt Only Group

OTHER

For 28 days, this group will be asked to consume 150 g of yogurt with the breakfast meal. The yogurt will be provided by the researchers. Apart from consuming the yogurt, this group will be asked to continue their normal lifestyle.

Dietary Supplement: Yogurt

Interventions

Exercise Snacking BEHAVIORAL

Each bout of exercise snacking consists of 5 exercise. Each exercise is performed for one minute, with aim of completing as many repetitions as possible of that exercise in that minute. One minute of rest is observed between each exercise of the exercise snack. The five exercises are; sit-to-stand from a chair, marching on the spot, seated knee extensions alternating legs, standing knee bends alternating legs, and standing calf raises. The sit-to-stand exercise is always performed first, with the number of repetitions achieved recorded, and subsequent exercises performed in any order without recording of repetitions. Two exercise snacks are completed each day for 28 days; once in the morning and once in the evening, or at least separated by 2 hours.

Exercise Snacking Group

Yogurt DIETARY_SUPPLEMENT

Participants are asked to consume 150 g of yogurt (Arla, Skyr- natural flavour) with their breakfast meal. Participants may substitute the yogurt for another part of their regular breakfast, or add the yogurt to their regular breakfast, with participants asked to record a log book of daily yogurt consumption and to complete a three day food diary during the last week of the 28 day intervention period.

Exercise Snacking Group; Yogurt Only Group

Eligibility Criteria

• Age: 65 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• Not underweight or obese (body mass index ≥20 and ≤ 30 kg/m2)
• Not regularly engaging in recreational sports or structured exercise (once a week or more).
• Non-smoker (for \>5 years)

You may not qualify if:

• Any chronic illness, cardiac, pulmonary, liver, or kidney abnormalities, uncontrolled hypertension, peripheral arterial disease, insulin- or non-insulin dependent diabetes or other metabolic disorders - all ascertained through preliminary screening.
• Individuals with a history of bone, joint or neuromuscular problems or a current musculoskeletal injury ascertained through preliminary screening.
• Individuals with any joint replacement surgical implants or other artifacts containing metal.
• Individuals with a clinically diagnosed allergy or intolerance of dairy products.
• Individuals with contraindications to exercise including chest pain, dizziness, or loss of consciousness, or who have been instructed by their doctor to only do physical activity recommended by them.
• Individuals who score less than 8 on the Short Physical Performance Battery or score zero on any component of the test.

Sponsors & Collaborators

• University of Bath: lead

Study Sites (1)

University of Bath

Bath, Avon, BA2 7AY, United Kingdom

Location

MeSH Terms

Interventions

Yogurt

Intervention Hierarchy (Ancestors)

Cultured Milk Products; Milk; Beverages; Diet, Food, and Nutrition; Physiological Phenomena; Fermented Foods; Dairy Products; Food; Food and Beverages

Study Officials

• Keith Stokes, PhD

  University of Bath

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principle Investigator

Study Record Dates

• First Submitted: December 6, 2016
• First Posted: December 14, 2016
• Study Start: November 20, 2016
• Primary Completion: June 1, 2017
• Study Completion: July 1, 2017
• Last Updated: May 23, 2018

Record last verified: 2018-05

Data Sharing

• IPD Sharing: Will not share

Locations

GB (1)