Retrospective Review of Mechanically Ventilated Patients Using a Continuous Data Collection System.

NCT02184208 | Completed Results

• 1 other identifier: IRB-P000011819
• Study Type: observational
• Target: 278
• Locations: 1 country
• Sites: 1

Brief Summary

Today, the electronic medical record, microprocessor mechanical ventilators, and physiologic monitoring are under-utilized when translating research into decision support. Current medical informatic capabilities can be leveraged to calculate trends in measured parameters to initiate a paradigm shift in critical care from reaction-based treatment to proactive and plausibly preventative care. Therefore, the purpose of this study is to develop baseline understanding of our practice and how data collection utilizing a newly implemented system called T3. We would like to retrospectively review mechanically ventilated patients in which we have collected continuous data to test a newly developed analytic platform. Additionally we would like to compare these results to our standards of practice established by clinical practice guidelines.

Conditions

Mechanical Ventilation; Acute Respiratory Distress Syndrome; Hypoxic Respiratory Failure

Keywords

ARDS; ALI; mechanical ventilation

Outcome Measures

Primary Outcomes (1)

• Successful Extubation

  Successful extubation without the use of noninvasive ventilation or requiring reintubation

  Within 24 hours of extubation

Study Arms (2)

Device utlization following extubation

Pulmonary mechanics

Eligibility Criteria

• Age: 1 Day - 35 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

All mechanically ventilated patients in our medical surgical ICU.

You may qualify if:

• Patient selection will be determined by available data collected in the T3 system. We estimate 50 patients in which mechanical ventilator data has been collected utilizing the limited intellibridge modules (4 systems currently available to collect ventilator data).

You may not qualify if:

• Patient not connected to T3 data collection system.

Sponsors & Collaborators

• Boston Children's Hospital: lead

Study Sites (1)

Boston Children's Hospital

Boston, Massachusetts, 02115, United States

Location

Related Publications (3)

• Castineira D, Schlosser KR, Geva A, Rahmani AR, Fiore G, Walsh BK, Smallwood CD, Arnold JH, Santillana M. Adding Continuous Vital Sign Information to Static Clinical Data Improves the Prediction of Length of Stay After Intubation: A Data-Driven Machine Learning Approach. Respir Care. 2020 Sep;65(9):1367-1377. doi: 10.4187/respcare.07561.

  PMID: 32879034 DERIVED

• Walsh BK, Smallwood C, Rettig J, Kacmarek RM, Thompson J, Arnold JH. Daily Goals Formulation and Enhanced Visualization of Mechanical Ventilation Variance Improves Mechanical Ventilation Score. Respir Care. 2017 Mar;62(3):268-278. doi: 10.4187/respcare.04873. Epub 2017 Jan 10.

  PMID: 28073993 DERIVED

• Walsh BK, Smallwood CD, Rettig JS, Thompson JE, Kacmarek RM, Arnold JH. Categorization in Mechanically Ventilated Pediatric Subjects: A Proposed Method to Improve Quality. Respir Care. 2016 Sep;61(9):1168-78. doi: 10.4187/respcare.04723. Epub 2016 Jun 14.

  PMID: 27303050 DERIVED

MeSH Terms

Conditions

Respiratory Distress Syndrome

Condition Hierarchy (Ancestors)

Lung Diseases; Respiratory Tract Diseases; Respiration Disorders

Results Point of Contact

• Title: Brian Kendall Walsh
• Organization: Boston Children's Hospital

brian.walsh@childrens.harvard.edu

617-919-3692

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Coordinator / Research Associate

Study Record Dates

• First Submitted: July 2, 2014
• First Posted: July 9, 2014
• Study Start: January 17, 2014
• Primary Completion: December 30, 2016
• Study Completion: January 9, 2017
• Last Updated: February 5, 2018
• Results First Posted: February 5, 2018

Record last verified: 2017-07

Locations

US (1)