Trials Sponsors Conditions Drugs Pricing

Conditions

Coarctation of the Aorta Tetralogy of Fallot Transposition of the Great Arteries

Keywords

Atria, HeartFunction, AtrialHeart Defects, CongenitalCardiovascular AbnormalitiesCongenital AbnormalitiesTetralogy, FallotTransposition of Great ArteriesCoarctation of the Aorta

Outcome Measures

Primary Outcomes (1)

Right and left atrial volume
Measurement of maximal volume (at end of systole), volume before atrial contraction (in late diastole), and minimal volume (at end of diastole) of both atria.
Day of CMR (baseline only, no intervention)

Secondary Outcomes (1)

Blood flow across the atrio-ventricular valves
Day of CMR (baseline only, no intervention)

Study Arms (2)

Tetralogy of Fallot

Patients after repair of tetralogy of Fallot

Normal

Normal controls

Eligibility Criteria

Age8 Years+

Sexall

Healthy VolunteersYes

Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

Participants for the study will be recruited among patients, children and adults, with CHD (groups 1-4) undergoing cardiac magnetic resonance examination for clinical reasons. 1. Patients after repair of coarctation of the aorta 2. Patients after repair of tetralogy of Fallot 3. Patients with transposition of the great arteries after atrial switch (Senning procedure) 4. Patients with transposition of the great arteries after arterial switch operation 5. Children without cardiovascular anomalies undergoing CMR for other clinical reasons not influencing cardiac function (control group)

You may qualify if:

Sponsors & Collaborators

University Children's Hospital, Zurich
Otherlead

Study Sites (1)

University Children's Hospital Zürich, Switzerland

Zurich, Canton of Zurich, 8032, Switzerland

MeSH Terms

Conditions

Aortic CoarctationTetralogy of FallotTransposition of Great VesselsHeart Defects, CongenitalCardiovascular AbnormalitiesCongenital Abnormalities

Condition Hierarchy (Ancestors)

Cardiovascular DiseasesHeart DiseasesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

Emanuela R Valsangiacomo Buechel, Prof.
University Children's Hospital Zürich, Switzerland
PRINCIPAL INVESTIGATOR

Enrollment

22 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

June 10, 2014

First Posted

June 11, 2014

Study Start

June 16, 2009

Actual (reported)

Haemodynamics and Function of the Atria in Congenital Heart Disease by Cardiovascular Magnetic Resonance

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (2)

Tetralogy of Fallot

Normal

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Study Arms (2)

Tetralogy of Fallot

Normal

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations