NCT02161029

Brief Summary

The purpose of this study is to determine whether the newly constructed CE (Conformité Européenne) marked drill biopsy instrument for flexible endoscopes can make possible representative biopsies of the increasing numbers of submucosal tumours in the gastrointestinal tract. The amount of submucous tissue ( micrograms and in % of all the biopsy) harvested with the new drill biopsy instrument used in flexible endoscopy investigations is measured in the study and compared to the amount of submucous tissue harvested with the existing biopsy forceps.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2014

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 25, 2014

Completed
3 months until next milestone

First Posted

Study publicly available on registry

June 11, 2014

Completed
21 days until next milestone

Study Start

First participant enrolled

July 2, 2014

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 27, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 27, 2015

Completed
Last Updated

February 1, 2019

Status Verified

January 1, 2019

Enrollment Period

9 months

First QC Date

March 25, 2014

Last Update Submit

January 30, 2019

Conditions

Keywords

Gastric tumor

Outcome Measures

Primary Outcomes (1)

  • Amount of submucous tissue in gastrointestinal submucosal tumors harvested with a new drill biopsy instrument used with flexible endoscopes.

    Amount of submucous tissue adequate for histological examination harvested with the new drill biopsy instrument for flexible endoscopy and compared to the amount harvested with the existing biopsy forceps in a randomized setting.

    Within 30 days for each patient

Study Arms (2)

New drill biopsy instrument

ACTIVE COMPARATOR

To take biopsies from gastric submucosal tumors with a new drill biopsy instrument used with flexible endoscopes.

Device: Flexible drill biopsy instrument

Conventional biopsy instrument

ACTIVE COMPARATOR

To take biopsies from gastric submucosal tumors with conventional biopsy forceps used with flexible endoscopes

Device: conventional biopsy instrument

Interventions

Biopsies taken with the new drill biopsy instrument for flexible endoscopy

Also known as: Endodrill (=Internal code name)
New drill biopsy instrument

Biopsies taken with conventional biopsy forceps for flexible endoscopic instruments

Conventional biopsy instrument

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Submucous gastrointestinal tumours

You may not qualify if:

  • No gastrointestinal submucous tumor
  • Submucosal hemangioma

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Surgery, Lund University

Lund, SE-22185, Sweden

Location

Related Links

MeSH Terms

Conditions

Stomach Neoplasms

Condition Hierarchy (Ancestors)

Gastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesStomach Diseases

Study Officials

  • Bruno S Walther, MD

    Professor

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

March 25, 2014

First Posted

June 11, 2014

Study Start

July 2, 2014

Primary Completion

March 27, 2015

Study Completion

March 27, 2015

Last Updated

February 1, 2019

Record last verified: 2019-01

Locations