NCT01832246

Brief Summary

The accurate prediction of depth of tumor invasion in early gastric cancer is essential for the proper selection of candidates for endoscopic resection. Conventional endoscopy and endoscopic ultrasonography have been useful diagnostic method for depth of invasion in early gastric cancer. However, there has been no prospective comparative study on the accuracy between the 2 methods. Therefore, the investigators prospectively compare the accuracy between the 2 methods regarding prediction of depth of invasion.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
560

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Dec 2014

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 4, 2012

Completed
10 months until next milestone

First Posted

Study publicly available on registry

April 16, 2013

Completed
1.6 years until next milestone

Study Start

First participant enrolled

December 1, 2014

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2015

Completed
Last Updated

November 18, 2014

Status Verified

November 1, 2014

Enrollment Period

1 year

First QC Date

July 4, 2012

Last Update Submit

November 17, 2014

Conditions

Keywords

endoscopyendosonographystomach cancertumor staging

Outcome Measures

Primary Outcomes (1)

  • diagnostic accuracy between endoscopic ultrasonographic staging and conventional endoscopic staging

    up to 2.5 years (end of study, December 2014)

Eligibility Criteria

Age20 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

patients with early gastric adenocarcinoma is prospectively enrolled at Seoul National University Hospital.

You may qualify if:

  • Patients with early gastric adenocarcinoma undergo both endoscopic staging and endoscopic ultrasonographic staging for depth of invasion

You may not qualify if:

  • patients had previously received neoadjuvant chemotherapy or chemoradiotherapy
  • patients with obviously advanced gastric cancer by endoscopy
  • the evidence of distant metastasis or extensive adjacent organ invasion on abdominal CT scan

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital

Seoul, Seoul, 110-744, South Korea

Location

MeSH Terms

Conditions

Stomach Neoplasms

Condition Hierarchy (Ancestors)

Gastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesStomach Diseases

Study Officials

  • Sang Gyun Kim, M.D.

    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine

    STUDY DIRECTOR
  • Jeongmin Choi, M.D.

    Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Jeongmin Choi, M.D.

CONTACT

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
professor, Department of Internal Medicine and Liver Research Institute

Study Record Dates

First Submitted

July 4, 2012

First Posted

April 16, 2013

Study Start

December 1, 2014

Primary Completion

December 1, 2015

Study Completion

December 1, 2015

Last Updated

November 18, 2014

Record last verified: 2014-11

Locations