Effects of Aerobic Exercise Detraining

NCT02158130 | Completed

• 1 other identifier: PBRC 2014-028
• Study Type: observational
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

The proposed study seeks to better understand the role of body weight, energy expenditure, and energy intake as mechanisms of body weight gain during detraining following aerobic exercise. It is hypothesized that participants in the higher dose exercise group will have greater body weight gain compared to the lower exercise dose and control group from wk 24 to wk 76 follow-up.

Conditions

Motor Activity; Body Weight; Obesity

Keywords

Physical Inactivity; Aerobic Exercise Detraining; Body Weight; Energy Expenditure; Metabolic Syndrome

Outcome Measures

Primary Outcomes (1)

• Body Weight

  Fasting body weight

  Week 64 - 88 post study randomization

Secondary Outcomes (2)

• Energy Expenditure

  Week 64 - 90 since study randomization

• Energy Intake

  Week 64 - 90 post study randomization

Other Outcomes (5)

• Circumferences

  Week 64-88 post study randomization

• Blood Pressure

  Week 64-88 post study randomization

• Body Composition

  Week 64 - 88 post study randomization

Study Arms (3)

Healthy Living

non exercise healthy living control group

General Health

Exercise Group (8 KKW) One exercise group will obtain 8KKW (kcal/kg/week) over 3-4 sessions per week, which will result in each session lasting approximately 30 minutes. We will recruit 1 year post study intervention.

Weight Loss

Exercise Group (20 KKW) Exercise group will obtain 20 KKW, perform in 4-5 sessions per week for approximately 50-70 minutes per session. We will recruit 1 year post study intervention.

Eligibility Criteria

• Age: 18 Years - 67 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participants that successfully enrolled and completed the E-Mechanic study and are not past 88 weeks study randomization.

You may qualify if:

• Completed the E-Mechanic study
• Be willing to archive blood samples
• Not participating in a study that would alter body weight, energy intake, or energy expenditure.

Sponsors & Collaborators

• Pennington Biomedical Research Center: lead

Study Sites (1)

Pennington Biomedical Research Center

Baton Rouge, Louisiana, 70808, United States

Location

Biospecimen

Retention: SAMPLES WITH DNA

serum, plasma

MeSH Terms

Conditions

Motor Activity; Body Weight; Obesity; Sedentary Behavior; Metabolic Syndrome

Condition Hierarchy (Ancestors)

Behavior; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Insulin Resistance; Hyperinsulinism; Glucose Metabolism Disorders; Metabolic Diseases

Study Officials

• John W Apolzan, PhD

  PBRC

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: June 4, 2014
• First Posted: June 6, 2014
• Study Start: September 1, 2014
• Primary Completion: March 1, 2016
• Study Completion: March 1, 2016
• Last Updated: March 22, 2016

Record last verified: 2016-03

Locations

US (1)