NCT02155959

Brief Summary

Abstract Purpose: To evaluate the visual performance and rotational stability of the Tecnis Toric one-piece IOL (AMO, USA) during the first 3 post-operative months Design: Prospective single center study Setting: VIROS - Vienna Institute for Research in Ocular Surgery, a Karl Landsteiner Institute, Hanusch Hospitel, Vienna, Austria Methods: In this prospective study patients with age-related cataract and corneal astigmatism of 1.0 to 3.0 D measured with the IOL-Master 500 (Carl Zeiss Meditec AG, Germany) were included. Pre-operatively, rotating Scheimpflug scans (Pentacam HR, Oculus, Germany) were performed and the cornea was marked in the sitting position at the slit lamp. Patients recieved a single-piece toric hydrophobic acrylic IOL (Tecnis Toric, AMO, USA). Immediately and 3 months after surgery retroillumination photographs were taken to assess the rotational stability of the IOL. Additionally, Autorefraction (Topcon, USA), subjective refraction, uncorrected and distance corrected visual acuity, keratometry, Scheimpflug and ocular wavefront (WASCA, Carl Zeiss Meditec AG, Germany) measurements were performed at the 3 months follow-up.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Mar 2011

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2011

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2012

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

June 12, 2013

Completed
12 months until next milestone

First Posted

Study publicly available on registry

June 4, 2014

Completed
Last Updated

June 4, 2014

Status Verified

June 1, 2014

Enrollment Period

1.8 years

First QC Date

June 12, 2013

Last Update Submit

June 2, 2014

Conditions

Keywords

astigmatismcataracttoriclens

Outcome Measures

Primary Outcomes (1)

  • Rotational stability of the investigated toric lens

    Rotation of the investigated intraocular lens using a photograph technique (retroillumination images) immediately after surgery and 3 months later.

    3 months

Secondary Outcomes (1)

  • reduction in post-operative higher order aberrations

    3 months

Study Arms (1)

one group

one group receiving a toric intraocular lens during cataract surgery.

Device: toric intraocular lens

Interventions

toric intraocular lens

Also known as: Tecnis toric IOL (Abott Medical Optics, USA)
one group

Eligibility Criteria

Age21 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

patients who were scheduled for cataract surgery and had corneal astigmatism

You may qualify if:

  • corneal astigmatism between 1.0 D and 3.0 D
  • cataract

You may not qualify if:

  • irregular astigmatism
  • forme fruste Keratoconus
  • corneal scars
  • phakodonesis
  • pseudoexfoliation syndrome
  • traumatic cataract

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

CataractAstigmatism

Condition Hierarchy (Ancestors)

Lens DiseasesEye DiseasesRefractive Errors

Study Officials

  • Oliver Findl, MD, MBA

    Vienna Institute for Research in Ocular Surgery

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Prim. Prof. Dr., MBA

Study Record Dates

First Submitted

June 12, 2013

First Posted

June 4, 2014

Study Start

March 1, 2011

Primary Completion

December 1, 2012

Study Completion

December 1, 2012

Last Updated

June 4, 2014

Record last verified: 2014-06