Evaluating a Novel Working Memory Training Program to Decrease Symptoms of PTSD

NCT02139137 | Completed Results

• 1 other identifier: F31MH088170
• Study Type: interventional
• Target: 47
• Locations: 0 countries
• Sites: N/A

Brief Summary

The study is designed to evaluate the effect of a novel computer training program on PTSD.

Conditions

Posttraumatic Stress Disorder

Outcome Measures

Primary Outcomes (1)

• Change in Clinician Administered PTSD Scale; Re-experiencing

  Model estimations of the means and standard deviation of posttreatment score at the mean level of baseline severity reported below. Scale range: 0-40, higher values indicate greater symptom severity

  Baseline, Week 4

Secondary Outcomes (4)

• Clinician Administered PTSD Scale Total Score - Responder Status

  Week 4

• Change in Depression: Beck Depression Inventory

  Baseline, Week 4

• Change in General Anxiety: Spielberger State-Trait Anxiety Inventory

  Baseline, Week 4

• Change in Functional Impairment; Sheehan Disability Scale

  Baseline, Week 4

Study Arms (2)

High Interference Control Condition

EXPERIMENTAL

Computerized training program requiring participants to repeatedly practice controlling interference on a cognitive task

Other: Computerized Cognitive Training - active

Low Interference Control Condition

ACTIVE COMPARATOR

Computerized training program requiring participants to minimally practice controlling interference on a cognitive task

Other: Computerized cognitive training - sham

Interventions

Computerized Cognitive Training - active OTHER

Cognitive training using working memory span task

High Interference Control Condition

Computerized cognitive training - sham OTHER

Sham training condition

Low Interference Control Condition

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Female
• Age 18-65
• Primary DSM-IV diagnosis of PTSD secondary to sexual trauma

You may not qualify if:

• Current trauma or PTSD-focused psychosocial treatment
• Active suicidality, evidence of substance dependence in the past 6 months
• Evidence of current or past schizophrenia
• Bipolar disorder
• Organic mental disorder

Sponsors & Collaborators

• Rick Gulizia: lead

Related Publications (1)

• Bomyea J, Stein MB, Lang AJ. Interference control training for PTSD: A randomized controlled trial of a novel computer-based intervention. J Anxiety Disord. 2015 Aug;34:33-42. doi: 10.1016/j.janxdis.2015.05.010. Epub 2015 Jun 10.

  PMID: 26114901 RESULT

MeSH Terms

Conditions

Stress Disorders, Post-Traumatic

Condition Hierarchy (Ancestors)

Stress Disorders, Traumatic; Trauma and Stressor Related Disorders; Mental Disorders

Results Point of Contact

• Title: Jessica Bomyea
• Organization: SDSU/UCSD Joint Doctoral Program in Clinical Psychology

jbomyea@ucsd.edu

8585528585

Study Officials

• Jessica A Bomyea, M.S.

  San Diego State University/University of California, San Diego

  PRINCIPAL INVESTIGATOR

• Ariel J Lang, Ph.D.

  University of California, San Diego

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Director of Research Affairs

Study Record Dates

• First Submitted: May 12, 2014
• First Posted: May 15, 2014
• Study Start: January 1, 2010
• Primary Completion: August 1, 2013
• Study Completion: December 1, 2013
• Last Updated: November 6, 2017
• Results First Posted: March 7, 2017

Record last verified: 2017-10

Data Sharing

• IPD Sharing: Will not share