Effect of Adaptive Training for Balance Recovery
Perturbation Training for Fall-risk Reduction Among Older Adults
2 other identifiers
interventional
308
1 country
1
Brief Summary
The long-term objective of this research is a prophylactic approach that can reduce the incidence of falls and the resulting injuries among older adults at risk and thus reduce its escalating medical cost. This project explores perturbation training through the use of treadmill device and a motor learning approach, in which experience with slip-like perturbation generated by that treadmill is used to prepare the motor system to develop and then put to use fall-resisting skills outside of training environment (cross-environment transfer). The computer-controlled treadmill is portable, safe and easy to operate, thus conducive for use in clinics or community centers. The study logically builds on and complements the team's previous and current research programs, and will further test that after such a single session, older adults at risk can retain such cross-environment transfer and reduce their likelihood of falls in everyday living for the next 6 to 12 months. Finally, the study will explore that such reduction of falls does not come merely from these persons' familiarity with the training or testing setup, protocol and environments.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jun 2014
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 25, 2014
CompletedFirst Posted
Study publicly available on registry
April 30, 2014
CompletedStudy Start
First participant enrolled
June 1, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 15, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
December 15, 2022
CompletedMay 16, 2024
May 1, 2024
8.5 years
April 25, 2014
May 14, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Fall incidence
1 year
Secondary Outcomes (1)
Dynamic stability
6 months
Study Arms (3)
treadmill perturbation
EXPERIMENTALtreadmill slip perturbation
treadmill placebo
PLACEBO COMPARATORtreadmill training placebo
observation
SHAM COMPARATORobservation training
Interventions
Group A will receive perturbation training on a treadmill with precisely controlled slip-like displacements and then encounter an unannounced novel slip during over-ground walking.
An age-matched control group (Group B) will receive only placebo training (on the same treadmill for the same duration but without perturbation) but encounter an identical novel slip during their over-ground walking.
An age-matched observation-training group (Group C) will watch a training video and slides. When exposed to an identical novel slip in over-ground walking, they will know where and how the slip is going to occur and how to resist a fall.
Eligibility Criteria
You may qualify if:
- Subjects with no known history of musculoskeletal, neurological, cardiovascular, or pulmonary impairment that may affect their ability to perform the testing procedures will be included.
You may not qualify if:
- Ultrasound calcaneus bone mineral density T score \< -2.5 (osteoporotic)
- Mini-Mental State exam score \< 25 (cognitive impairment)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Clinical Gait and Movement Analysis Laboratory
Chicago, Illinois, 60612, United States
Related Publications (1)
Wang Y, Wang S, Liu X, Lee A, Pai YC, Bhatt T. Can a single session of treadmill-based slip training reduce daily life falls in community-dwelling older adults? A randomized controlled trial. Aging Clin Exp Res. 2022 Jul;34(7):1593-1602. doi: 10.1007/s40520-022-02090-3. Epub 2022 Mar 2.
PMID: 35237948DERIVED
Study Officials
- PRINCIPAL INVESTIGATOR
Tanvi Bhatt, PhD
University of Illinois at Chicago
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
April 25, 2014
First Posted
April 30, 2014
Study Start
June 1, 2014
Primary Completion
December 15, 2022
Study Completion
December 15, 2022
Last Updated
May 16, 2024
Record last verified: 2024-05