National Registry for Egyptian Pediatric Neuromuscular Diseases

NCT02124616 | Unknown DMC

• 1 other identifier: EGYPT PED-NMD 2014
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

Our aim is to establish multi-center national Egyptian database of information for inherited and acquired neuromuscular diseases in infants and children from 0 to 18 years of age.

Conditions

Spinal Muscular Atrophy; Muscular Dystrophy; Muscle Diseases; Myasthenic Syndromes; Polyneuropathies

Keywords

spinal muscular atrophy; Muscular dystrophy; Muscle diseases; myasthenic syndromes; Polyneuropathies; Myopathies

Outcome Measures

Primary Outcomes (1)

• Functional motor ability

  Motor power in acquired acute neuromuscular diseases will be assessed at admission and morbidity and mortality at discharge from hospital. Functional motor ability will be performed every 3 months for children with inherited neuromuscular diseases.

  1 year

Secondary Outcomes (1)

• Cardio-pulmonary function

  12 months

Study Arms (1)

Neuromuscular diseases

Prospective cohort of children with inherited or acquired neuromuscular diseases.

Eligibility Criteria

• Age: 1 Month - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

All children from birth to 18 years of age with inherited or acquired neuromuscular diseases.

You may qualify if:

• Weakness, hypotonia.
• Nerve conduction study and electromyographic confirmation of lower motor neuron affection.

You may not qualify if:

• Chromosomal diseases.
• Malformations and deformations.

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Pediatric Department, Children's Hospital, Faculty of Medicine, Ain Shams University

Cairo, Abassia, 11381, Egypt

RECRUITING

Related Links

• Faculty of Medicine, Ain Shams University website
• Ain Shams University web site

MeSH Terms

Conditions

Muscular Atrophy, Spinal; Muscular Dystrophies; Lambert-Eaton Myasthenic Syndrome; Polyneuropathies; Muscular Diseases

Condition Hierarchy (Ancestors)

Spinal Cord Diseases; Central Nervous System Diseases; Nervous System Diseases; Motor Neuron Disease; Neurodegenerative Diseases; Neuromuscular Diseases; Muscular Disorders, Atrophic; Musculoskeletal Diseases; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Myasthenia Gravis; Paraneoplastic Syndromes, Nervous System; Nervous System Neoplasms; Neoplasms by Site; Neoplasms; Paraneoplastic Syndromes; Autoimmune Diseases of the Nervous System; Neuromuscular Junction Diseases; Autoimmune Diseases; Immune System Diseases; Peripheral Nervous System Diseases

Study Officials

• Sahar MA Hassanein, MD, PhD

  Pediatric Department, Children's Hospital, Faculty of Medicine, Ain Shams University

  STUDY CHAIR

Central Study Contacts

Sahar MA Hassanein, MD, PhD

CONTACT

201223183943; saharhassanein@med.asu.edu.eg

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Target Duration: 5 Years
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Pediatrics

Study Record Dates

• First Submitted: April 25, 2014
• First Posted: April 28, 2014
• Study Start: April 1, 2014
• Primary Completion: April 1, 2020
• Study Completion: December 1, 2020
• Last Updated: April 28, 2014

Record last verified: 2014-04

Locations

EG (1)