Zoonotic Influenza Infections of Swine Origin at Ohio Agricultural Fairs

Background: \- The flu is a very infectious and contagious virus that affects both people and pigs. Studies show that pigs can be sources of the flu virus in humans. Researchers want to know more about how the flu is transmitted from animals to people. If they know more about it, they can find better ways to prevent the flu and treat people who get sick from it. Objective: \- To discover if flu viruses can be found in people exposed to pigs at Ohio agricultural fairs. Eligibility: \- Volunteers 8 years of age and older who exhibit pigs at Ohio agricultural fairs. Design:

• Before or on the first day of the fair, participants will fill out a short demographic and medical history form. They will also complete a two-page symptom questionnaire. This is a form that asks them about any flu symptoms they might have.
• Participants will have a nasal swab performed. The inside of the participant s nose will be rubbed with a swab to collect nasal fluid.
• Researchers will see participants 2 days later and 4 days later. During these visits, participants will again fill out a symptom questionnaire and have a nasal swab.