NCT02090257

Brief Summary

The purpose of this pilot trial, Transitioning to Adult Care (TRANSIT), is to develop and test an intervention (i.e., a standardized, tailored transition program focused on enhancing adherence) to improve outcomes for emerging adults who underwent heart transplantation as children and transfer to adult care.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
88

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Mar 2014

Longer than P75 for not_applicable

Geographic Reach
1 country

6 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2014

Completed
4 days until next milestone

First Submitted

Initial submission to the registry

March 5, 2014

Completed
13 days until next milestone

First Posted

Study publicly available on registry

March 18, 2014

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2016

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2017

Completed
Last Updated

July 26, 2017

Status Verified

July 1, 2017

Enrollment Period

2.3 years

First QC Date

March 5, 2014

Last Update Submit

July 25, 2017

Conditions

Keywords

Heart transplant recipients who are entering into adult care.

Outcome Measures

Primary Outcomes (1)

  • To assess the feasibility of TRANSIT by measuring the transition program adherence for those randomized to the intervention and survey completion for all participants.

    Investigators hypothesize that by the end of the 3 month transition program and 6 months of follow-up, 84% of patients will be retained; 80% will participate in the program (module completion, discussion, and follow-up); and 100% will complete at least 80% of the survey instruments at each data collection point.

    6 months

Secondary Outcomes (2)

  • To determine the efficacy of TRANSIT on patient-level outcomes .

    6 months

  • To determine the efficacy of TRANSIT on meso-level outcomes.

    6 Months

Study Arms (2)

TRANSIT, behavioral

EXPERIMENTAL

The intervention group will receive more guidance during their transition from a pediatric center to the adult center

Behavioral: TRANSIT

Usual Care Group

NO INTERVENTION

The usual care group will receive a standard transfer of care from a pediatric center to an adult center.

Interventions

TRANSITBEHAVIORAL

Educational Modules, staff follow up.

TRANSIT, behavioral

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Have received a heart transplant at a children's hospital and are ready to transition, as determined by the pediatric heart transplant cardiologist, to the adult heart transplant center with whom a collaborative relationship has been established;
  • years or older;
  • Able to speak, read at a fifth grade level or above, and write English;
  • Physically able to participate.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Loma Linda University

Loma Linda, California, 92354, United States

Location

Universtiy of Colorado Denver/Children Colorado

Aurora, Colorado, 80045, United States

Location

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, 60611, United States

Location

Northwestern Memorial Hospital

Chicago, Illinois, 60611, United States

Location

Columbia University

New York, New York, 10032, United States

Location

Children's Hospital of Philadelphia/University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

Location

Study Officials

  • Elfriede Pahl, MD

    Ann and Robert Lurie Children's Hospital

    PRINCIPAL INVESTIGATOR
  • Kathleen Grady, PhD

    Northwestern University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Attending Physician, Division of Cardiology

Study Record Dates

First Submitted

March 5, 2014

First Posted

March 18, 2014

Study Start

March 1, 2014

Primary Completion

May 31, 2016

Study Completion

May 31, 2017

Last Updated

July 26, 2017

Record last verified: 2017-07

Locations