Bipolar Research Study Using MR Imaging
Neuromorphometry of Psychosis in Bipolar Disorder
1 other identifier
observational
75
1 country
1
Brief Summary
In this proposal, the investigators will focus on subcortical gray and white matter structures commonly found to be abnormal in schizophrenia. Thus, the investigators will evaluate the volume and shape of the hippocampus, thalamus and basal ganglia, as well as measures of structural integrity of the corpus callosum and its various subregions.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jan 2010
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2010
CompletedFirst Submitted
Initial submission to the registry
March 7, 2014
CompletedFirst Posted
Study publicly available on registry
March 11, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2014
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2014
CompletedJune 3, 2015
June 1, 2015
4.9 years
March 7, 2014
June 1, 2015
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
subcortical grey and white matter structures
Evaluation of the volume and shape of the hippocampus, thalamus and basal ganglia, as well as measures of structural integrity of the corpus callosum and its various subregions.
within one month of study enrollment
Study Arms (2)
Bipolar Diagnosis
Individuals identified as having a Bipolar Diagnosis with a manic episode
Control
Individuals identified as not having a major psychiatric diagnosis
Interventions
Eligibility Criteria
Community Sample
You may qualify if:
- between the ages of 18-30
- diagnosed with Bipolar Disorder
You may not qualify if:
- history of head injury
- unstable medical condition
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Washington University School of Medicine
St Louis, Missouri, 63110, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Daniel Mamah, M.D, MPE
Washington University School of Medicine
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 7, 2014
First Posted
March 11, 2014
Study Start
January 1, 2010
Primary Completion
December 1, 2014
Study Completion
December 1, 2014
Last Updated
June 3, 2015
Record last verified: 2015-06