NCT02083393

Brief Summary

To observe changes of circulating and tissue dendritic cells in acute lung injury,including invasive aspergillosis pneumonia

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
19

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jun 2011

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2011

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

September 28, 2011

Completed
2.5 years until next milestone

First Posted

Study publicly available on registry

March 11, 2014

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2014

Completed
Last Updated

May 27, 2015

Status Verified

May 1, 2015

Enrollment Period

3.5 years

First QC Date

September 28, 2011

Last Update Submit

May 26, 2015

Conditions

Acute Lung Injury

Keywords

dendritic cell

Outcome Measures

Primary Outcomes (1)

  • 28-day mortality

    28day

Study Arms (2)

Patients with acute lung injury

Patients with sepsis induced acute lung injury

Postsurgery patients

Postsurgery patients without acute lung injury and sepsis

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Sepsis induced-ALI patients with mechanical ventilation including invasive aspergillosis

You may qualify if:

  • Sepsis induced acute lung injury

You may not qualify if:

  • Younger than 18-year-old
  • Pregnancy
  • Cancer or organ transplant
  • Asthma
  • COPD
  • Heart Failure

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Zhongda Hospital Southeast University

Nanjing, Jiangsu, 210000, China

Location

MeSH Terms

Conditions

Acute Lung Injury

Condition Hierarchy (Ancestors)

Lung InjuryLung DiseasesRespiratory Tract Diseases

Study Officials

  • Haibo Qiu, Ph.D.

    Southeast University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Zhongda Hospital

Study Record Dates

First Submitted

September 28, 2011

First Posted

March 11, 2014

Study Start

June 1, 2011

Primary Completion

December 1, 2014

Study Completion

December 1, 2014

Last Updated

May 27, 2015

Record last verified: 2015-05

Locations

CN(1)