Mushroom Blend on Oxygen Kinetics

NCT02075892 | Completed

• 1 other identifier: 14-0062
• Study Type: interventional
• Target: 28
• Locations: 1 country
• Sites: 1

Brief Summary

Purpose: To determine the acute effects of a mushroom blend vs. placebo on oxygen kinetics, aerobic power and time to fatigue in healthy adults.

Conditions

Oxygen Utilization; Oxygen Kinetics

Keywords

cordyceps, aerobic capacity, exercise performance, fatigue

Outcome Measures

Primary Outcomes (2)

• Oxygen kinetics

  oxygen uptake and utilization using indirect calorimetry during a 6 min steady-state exercise bout

  during a 6 min

• Critical Power

  3 min all-out cycling test to measure anaerobic and aerobic performance

  during a 3 min

Secondary Outcomes (3)

• Lactate

  baseline, 2min, 3min, 6min (pre-post supplementation)

• Cortisol

  during a 6 min

• Maximal Oxygen Consumption

  during a graded exercise test to exhaustion

Study Arms (2)

Mushroom Blend

ACTIVE COMPARATOR

4 grams daily; oral; 7 and 21 days

Dietary Supplement: Mushroom Blend

Placebo

PLACEBO COMPARATOR

4 grams maltodextrin, oral, 7 and 21 days

Dietary Supplement: Placebo

Interventions

Mushroom Blend DIETARY_SUPPLEMENT

Scivation

Also known as: Cordyceps

Mushroom Blend

Placebo DIETARY_SUPPLEMENT

Placebo

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Participant has been involved in exercise program for a minimum of one year prior to recruitment (≥ 3 d/wk)
• Participant is able to exercise (i.e. no existing musculoskeletal injury)
• Participant is willing and able to comply with the protocol
• Participant is apparently healthy and free from disease, as determined by a health history questionnaire and physical
• Participant agrees to abstain from smoking, caffeine, tobacco, and alcohol before testing days
• Participant agrees to abstain from exercise 24 hours prior to each testing visit
• Participant is not allergic to mushrooms

You may not qualify if:

• Having a history of medical or surgical events that may significantly affect the study outcome, including cardiovascular disease, metabolic, renal, hepatic, or musculoskeletal disorders
• Participant is using, or has used one of the following dietary supplements within 12 weeks prior to enrollment: Beta-alanine, Creatine, Carnosine or Taurine
• Participant has lost or gained greater than ten pounds within the previous 3 month
• Participant is currently enrolled in another clinical trial.
• Participant has a known allergy or sensitivity to any ingredient in the test product or placebo (determined from health history questionnaire)

Sponsors & Collaborators

• University of North Carolina, Chapel Hill: lead
• Scivation, Inc: collaborator

Study Sites (1)

Applied Physiology Laboratory, Fetzer Hall

Chapel Hill, North Carolina, 27599, United States

Location

MeSH Terms

Conditions

Fatigue

Condition Hierarchy (Ancestors)

Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Abbie Smith-Ryan, PhD

  University of North Carolina

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 27, 2014
• First Posted: March 3, 2014
• Study Start: August 1, 2014
• Primary Completion: December 1, 2014
• Study Completion: December 1, 2014
• Last Updated: December 4, 2014

Record last verified: 2014-08

Locations

US (1)