NCT02075775

Brief Summary

This project will be a multi-center, prospective longitudinal cohort for all patients undergoing primary shoulder instability surgery, excluding isolated SLAP repairs. We will be looking for risk factors for recurrent instability, revision surgery, and poor outcomes. Patients will be asked to complete the RAND-36, ASES, Shoulder Activity, EQ-5D and WOSI outcome measures, as well as demographic and socioeconomic information. Surgeons will complete a form after surgery with information on radiographic findings, physical exam, surgical findings, and the repair. Patients will wear a sling post-operatively, and follow standardized rehabilitation protocols, including physical therapy. Patients will be sent outcome questionnaires at 2, 6, 10, and 20 years after surgery.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,733

participants targeted

Target at P75+ for all trials

Timeline
201mo left

Started Aug 2012

Longer than P75 for all trials

Geographic Reach
1 country

11 active sites

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress45%
Aug 2012Dec 2042

Study Start

First participant enrolled

August 1, 2012

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

February 27, 2014

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 3, 2014

Completed
18.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2032

Expected
9.9 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2042

Last Updated

April 8, 2026

Status Verified

April 1, 2026

Enrollment Period

20.4 years

First QC Date

February 27, 2014

Last Update Submit

April 2, 2026

Conditions

Keywords

instability

Outcome Measures

Primary Outcomes (1)

  • Predictors of worse patient outcomes (pain and/or reduced quality of life).

    Patients will fill out PRO's after surgery

    2 years, 6 years, 10 years and 20 years

Secondary Outcomes (1)

  • Predictors for recurrent instability

    2 years, 6 years, 10 years and 20 years

Other Outcomes (1)

  • Predictors of shoulder osteoarthritis

    6 years, 10 years and 20 years

Study Arms (1)

MOON Shoulder Instability

Patients indicated for Shoulder Instability surgery

Eligibility Criteria

Age12 Years - 99 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Potential subjects are patients who are undergoing surgery of the labrum and/or capsule for shoulder instability

You may qualify if:

  • This is a prospective cohort study; there is no control group. Subjects that are included are all patients undergoing surgery for shoulder instability.
  • Anterior, posterior, and inferior instability
  • Ages 12-99
  • Open and arthroscopic repair
  • Revision of a previous shoulder instability repair
  • Latarjet/bone augmentation

You may not qualify if:

  • Workers compensation patients
  • Prisoners
  • Non-English speaker
  • Not mentally competent
  • Unable/unwilling to return for clinical follow-up
  • Arthroplasty patients
  • Rotator cuff tears
  • Fractures

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (11)

UCSF Orthopedic Institute

San Francisco, California, 94158, United States

Location

University of Colorado

Boulder, Colorado, 80304, United States

Location

University of Iowa

Iowa City, Iowa, 52242, United States

Location

University of Kentucky

Lexington, Kentucky, 40536, United States

Location

Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States

Location

University of Michigan

Ann Arbor, Michigan, 48109-0328, United States

Location

Washington University

St Louis, Missouri, 63110, United States

Location

Hospital for Special Surgery

New York, New York, 10021, United States

Location

Ohio State University

Columbus, Ohio, 43221, United States

Location

Orthopedic Institute

Sioux Falls, South Dakota, 57105, United States

Location

Vanderbilt University

Nashville, Tennessee, 37232-8774, United States

Location

Related Publications (3)

  • Hettrich CM, Magnuson JA, Baumgarten KM, Brophy RH, Kattan M; MOON Shoulder Group; Bishop JY, Bollier MJ, Bravman JT, Cvetanovich GL, Dunn WR, Feeley BT, Frank RM, Kuhn JE, Lansdown DA, Benjamin Ma C, Marx RG, McCarty EC, Neviaser AS, Ortiz SF, Seidl AJ, Smith MV, Wright RW, Zhang AL, Cronin KJ, Wolf BR. Predictors of Bone Loss in Anterior Glenohumeral Instability. Am J Sports Med. 2023 Apr;51(5):1286-1294. doi: 10.1177/03635465231160286. Epub 2023 Mar 20.

  • Brophy RH, Dunn WR; MOON Shoulder Group; Baumgarten KM, Bishop JY, Bollier MJ, Bravman JT, Feeley BT, Grant JA, Jones GL, Kuhn JE, Benjamin Ma C, Marx RG, McCarty EC, Ortiz SF, Smith MV, Wolf BR, Wright RW, Zhang AL, Hettrich CM. Factors Associated With Shoulder Activity Level at Time of Surgery and at 2-Year Follow-up in Patients Undergoing Shoulder Stabilization Surgery. Am J Sports Med. 2022 May;50(6):1503-1511. doi: 10.1177/03635465221085978. Epub 2022 Apr 20.

  • Baron JE, Duchman KR, Hettrich CM, Glass NA, Ortiz SF; MOON Shoulder Group; Baumgarten KM, Bishop JY, Bollier MJ, Bravman JT, Brophy RH, Carpenter JE, Cox CL, Feeley BT, Frank RM, Grant JA, Jones GL, Kuhn JE, Lansdown DA, Benjamin Ma C, Marx RG, McCarty EC, Miller BS, Neviaser AS, Seidl AJ, Smith MV, Wright RW, Zhang AL, Wolf BR. Beach Chair Versus Lateral Decubitus Position: Differences in Suture Anchor Position and Number During Arthroscopic Anterior Shoulder Stabilization. Am J Sports Med. 2021 Jul;49(8):2020-2026. doi: 10.1177/03635465211013709. Epub 2021 May 21.

MeSH Terms

Conditions

Joint Dislocations

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal DiseasesWounds and Injuries

Study Officials

  • Carolyn M Hettrich, MD, MPH

    Brigham and Women's Hospital

    PRINCIPAL INVESTIGATOR
  • Brian Wolf, MD, MS

    University of Iowa

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
20 Years
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

February 27, 2014

First Posted

March 3, 2014

Study Start

August 1, 2012

Primary Completion (Estimated)

December 31, 2032

Study Completion (Estimated)

December 1, 2042

Last Updated

April 8, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations