NCT02069691

Brief Summary

Background: Hemiplegia is one of the main reasons why stroke survivors lose their walking and balancing ability. Many studies point out that cycling is an effective means for lower limb rehabilitation. However, during training, the unaffected limb may compensate for the affected one resulting in suboptimal rehabilitation. To address this issue, the investigators developed the virtual reality-cycling training system (VRCTS) which can acquire force and speed signals in real-time through a cycling module. The system then analyzes the acquired data and uses a 3D VR rehabilitation program to help patients to train their affected side. The aim of the study was to develop the VRCTS, verify its function and test system function on both normal subjects and stroke patients. Methods: In this system, the investigators designed a cycling device that is embedded with load cell and encoder sensors to detect cycling force and angle in real-time. A Cycling Graph User Interface Control and Data Recode System (Cycling CR System) was applied for signal analysis and feedback control. The investigators designed a 3D interactive VR rehabilitation program that can guide and train the users through visual feedback. Each user performed a pre-test to examine determine condition, left-right balance and other parameters, which allows the system to be customized.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
13

participants targeted

Target at below P25 for not_applicable stroke

Timeline
Completed

Started Aug 2012

Shorter than P25 for not_applicable stroke

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2012

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2012

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2013

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

February 17, 2014

Completed
7 days until next milestone

First Posted

Study publicly available on registry

February 24, 2014

Completed
Last Updated

February 24, 2014

Status Verified

August 1, 2012

Enrollment Period

2 months

First QC Date

February 17, 2014

Last Update Submit

February 20, 2014

Conditions

Keywords

stroke,rehabilitation,leg cycling,feedback,virtual reality

Outcome Measures

Primary Outcomes (1)

  • pedal force of affected leg

    up to 24 weeks

Secondary Outcomes (1)

  • asymmetrical ratio index

    up to 24 weeks

Study Arms (1)

virtual reality-cycling training system

EXPERIMENTAL
Device: virtual reality-cycling training system

Interventions

virtual reality-cycling training system

Eligibility Criteria

Age25 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • single stroke with unilateral hemiplegia (Brunnstrom stage III);
  • hypertonia in the affected leg, modified Ashworth scale (MAS) grade ≦ 2;
  • no significant perceptual, cognitive, or sensory deficits;
  • no history of osteoarthritis, severe cardiopulmonary disease, or vascular disease in lower limbs
  • lack of a fixed contracture in the affected lower limb

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Chung Shan Medical University Hospital

Taichung, 40201, Taiwan

Location

Related Links

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
pofessor

Study Record Dates

First Submitted

February 17, 2014

First Posted

February 24, 2014

Study Start

August 1, 2012

Primary Completion

October 1, 2012

Study Completion

May 1, 2013

Last Updated

February 24, 2014

Record last verified: 2012-08

Locations