Inferior Vena Cava (IVC) Size in Acute Renal Failure
Does the Inferior Vena Cava Size Assessment Help in the Management of Acute Kidney Injury in Critically Ill Patients?
1 other identifier
observational
33
1 country
1
Brief Summary
Bedside ultrasonographic assessment of IVC size and IVC collapsibility index can be used to guide the management of patients with acute kidney injury with and without volume overload in the intensive care unit
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Feb 2014
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2014
CompletedFirst Submitted
Initial submission to the registry
February 6, 2014
CompletedFirst Posted
Study publicly available on registry
February 17, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2016
CompletedJune 9, 2016
June 1, 2016
2.2 years
February 6, 2014
June 8, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
percentage of patients with improved Creatinine level in group 1 and 2
percentage of patients with improved Creatinine level in group 1 and 2
48 hours
Secondary Outcomes (1)
glomerular filtration rate (GFR), changes in hemodynamic parameters (mean arterial blood pressure, urine output, pressors requirement )and Partial oxygen pressure (PO2) /Fio2 in group 1 and group 2
24 and 48 hours
Study Arms (1)
Acute renal failure in ICU
Ultrasound for measurement of Inferior Vena Cava size
Interventions
Focused bedside ultrasound will be performed for each patient as part of their routine care and initial assessment. The IVC size will be measured at the subcostal window, during inspiration and expiration, using the Sonosite cardiac probe P-21 (5-1 MHZ). The measurement is obtained by applying the M-mode, perpendicular to the IVC axis and 2 cm caudal from its junction with the right atrium.
Eligibility Criteria
Consecutive patients presenting to the intensive care unit with a diagnosis of acute renal failure ( Defined as 1.5 fold increase in plasma creatinine level compared to baseline)
You may qualify if:
- patients presenting to the intensive care unit with a diagnosis of acute renal failure (defined as a 1.5 fold increase in plasma Creatinine level compared to baseline)
You may not qualify if:
- Age\<18 years
- Hemodialysis or continuous renal replacement therapy(CRRT)
- Untreated obstructive uropathy
- Pulmonary emboli
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104, United States
Related Publications (1)
Jambeih R, Keddissi JI, Youness HA. IVC Measurements in Critically Ill Patients with Acute Renal Failure. Crit Care Res Pract. 2017;2017:3598392. doi: 10.1155/2017/3598392. Epub 2017 Sep 5.
PMID: 29057120DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Houssein Youness, MD
University of Oklahoma
Study Design
- Study Type
- observational
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 6, 2014
First Posted
February 17, 2014
Study Start
February 1, 2014
Primary Completion
May 1, 2016
Study Completion
May 1, 2016
Last Updated
June 9, 2016
Record last verified: 2016-06