Qigong Intervention Program for Abused Chinese Women

NCT02060123 | Completed

• 1 other identifier: UW 12-555
• Study Type: interventional
• Target: 271
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to evaluate the effect of a qigong intervention program on telomerase activity in Chinese women with a history of intimate partner violence.

Conditions

Abused Women

Keywords

Qigong; Telomerase; Perceived stress; RCT; Chinese; Abused women; intervention; Depression

Outcome Measures

Primary Outcomes (1)

• Change in telomerase activity

  For each participant, 10 ml of peripheral blood will be collected for measurements of telomerase activity at two time points: pre-intervention (T0) and post-intervention (T2) in the intervention group, as well as in wait-list control group before qigong training.

  pre-intervention (baseline) and post-intervention (5.5 months later)

Secondary Outcomes (5)

• Change in level of pro-inflammatory cytokines

  pre-intervention (baseline) and post-intervention (5.5 months later)

• Change in perceived stress

  pre-intervention (baseline), post-training (6 weeks later) and post-intervention (5.5 months later)

• Change in perceived coping

  pre-intervention (baseline), post-training (6 weeks later) and post-intervention (5.5 months later)

• Change in depressive symptoms

  pre-intervention (baseline), post-training (6 weeks later) and post-intervention (5.5 months later)

• Change in sleep disturbance

  pre-intervention (baseline), post-training (6 weeks later) and post-intervention (5.5 months later)

Study Arms (2)

Qigong training

EXPERIMENTAL

a total of 103 hours over a period of 5.5 months, consisting of: * Group learning and practice: a 2-hour qigong exercise training session will be provided by a qigong master twice a week for six consecutive weeks (24 hours), * Weekly group follow-up: a 1-hour qigong exercise will be conducted with reinforcement of learning and remedial teaching by a qigong master once a week for four consecutive months (16 hours) after the group learning and practice, and * Self-practice: participant will engage in qigong exercise for 30 minutes every day for the whole intervention period lasting 5.5 months (63 hours).

Behavioral: Qigong training

Wait-list control- Health talks

OTHER

Monthly health education talks unrelated to qigong will be provided starting from the point when the intervention group starts the qigong weekly follow-up.Once the intervention group has completed the qigong intervention program, the wait-list control group will receive the qigong exercise training.

Other: Wait-list control- Health talks

Interventions

Qigong training BEHAVIORAL

a total of 103 hours over a period of 5.5 months, consisting of: * Group learning and practice: a 2-hour qigong exercise training session will be provided by a qigong master twice a week for six consecutive weeks (24 hours), * Weekly group follow-up: a 1-hour qigong exercise will be conducted with reinforcement of learning and remedial teaching by a qigong master once a week for four consecutive months (16 hours) after the group learning and practice, and * Self-practice: participant will engage in qigong exercise for 30 minutes every day for the whole intervention period lasting 5.5 months (63 hours).

Qigong training

Wait-list control- Health talks OTHER

Monthly health education talks unrelated to qigong will be provided starting from the point when the intervention group starts the qigong weekly follow-up.Once the intervention group has completed the qigong intervention program, the wait-list control group will receive the qigong exercise training.

Wait-list control- Health talks

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• years of age or older,
• willing to undertake the qigong intervention program,
• available for all testing points,
• receptive to random allocation, and
• assessed to be abused by an intimate partner in the preceding year or longer, based on the Chinese Abuse Assessment Screen.

You may not qualify if:

• had participated in qigong training or other mind body intervention within the previous 6 months, or
• have serious medical conditions that might limit their participation in qigong exercise (based on our previous experience, such conditions include cancer, severe obesity, narcolepsy, major depressive disorder, schizophrenia), or
• have psychiatric disorders, or
• use medication or other psychological intervention for stress, or
• are abused by someone who is not their intimate partner.

Sponsors & Collaborators

• The University of Hong Kong: lead

Study Sites (1)

HKSKH Lady MacLehose Center

Hong Kong, China

Location

Related Publications (7)

• Ho RT, Chan JS, Wang CW, Lau BW, So KF, Yuen LP, Sham JS, Chan CL. A randomized controlled trial of qigong exercise on fatigue symptoms, functioning, and telomerase activity in persons with chronic fatigue or chronic fatigue syndrome. Ann Behav Med. 2012 Oct;44(2):160-70. doi: 10.1007/s12160-012-9381-6.

  PMID: 22736201 BACKGROUND

• Zhang GD. The impacts of 48-form tai chi chuan and yi qi yang fei gong on the serum levels of IgG, IgM, IgA, and IgE in human. Journal of Beijing Institute of Physical Education. 1990;4:12-4.

  BACKGROUND

• Jahnke R, Larkey L, Rogers C, Etnier J, Lin F. A comprehensive review of health benefits of qigong and tai chi. Am J Health Promot. 2010 Jul-Aug;24(6):e1-e25. doi: 10.4278/ajhp.081013-LIT-248.

  PMID: 20594090 BACKGROUND

• Cheung DST, Chau PH, Yeung WF, Deng W, Hong AWL, Tiwari AFY. Assessing the effect of a mind-body exercise, qigong Baduanjin, on sleep disturbance among women experiencing intimate partner violence and possible mediating factors: a randomized-controlled trial. J Clin Sleep Med. 2021 May 1;17(5):993-1003. doi: 10.5664/jcsm.9102.

  PMID: 33551021 DERIVED

• Hameed M, O'Doherty L, Gilchrist G, Tirado-Munoz J, Taft A, Chondros P, Feder G, Tan M, Hegarty K. Psychological therapies for women who experience intimate partner violence. Cochrane Database Syst Rev. 2020 Jul 1;7(7):CD013017. doi: 10.1002/14651858.CD013017.pub2.

  PMID: 32608505 DERIVED

• Cheung DST, Deng W, Tsao SW, Ho RTH, Chan CLW, Fong DYT, Chau PH, Hong AWL, Fung HYKY, Ma JLC, Tiwari AFY. Effect of a Qigong Intervention on Telomerase Activity and Mental Health in Chinese Women Survivors of Intimate Partner Violence: A Randomized Clinical Trial. JAMA Netw Open. 2019 Jan 4;2(1):e186967. doi: 10.1001/jamanetworkopen.2018.6967.

  PMID: 30646209 DERIVED

• Tiwari A, Chan CL, Ho RT, Tsao GS, Deng W, Hong AW, Fong DY, Fung HY, Pang EP, Cheung DS, Ma JL. Effect of a qigong intervention program on telomerase activity and psychological stress in abused Chinese women: a randomized, wait-list controlled trial. BMC Complement Altern Med. 2014 Aug 15;14:300. doi: 10.1186/1472-6882-14-300.

  PMID: 25127878 DERIVED

MeSH Terms

Conditions

Depression

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior

Study Officials

• Agnes Tiwari, PhD

  The University of Hong Kong

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor and Head

Study Record Dates

• First Submitted: February 6, 2014
• First Posted: February 11, 2014
• Study Start: March 1, 2014
• Primary Completion: May 1, 2016
• Study Completion: May 1, 2016
• Last Updated: June 1, 2016

Record last verified: 2016-05

Locations

CN (1)