Prevention Ventilator Associated Pneumonia
REINA
Impact of 4 Sequential Measures on the Prevention of Ventilator Associated Pneumonia in Major Heart Surgery Intensive Care Unit
1 other identifier
interventional
1,534
1 country
1
Brief Summary
The objective of the investigators work was to evaluate the impact of 4 sequentially implemented measures for preventing VAP in a major heart surgery ICU. The measures were a specific training program, aspiration of subglottic secretions (ASS), introduction of an inclinometer to improve the semirecumbent position, and reinforcement of oral care with chlorhexidine.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Nov 2009
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 1, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2012
CompletedFirst Submitted
Initial submission to the registry
February 4, 2014
CompletedFirst Posted
Study publicly available on registry
February 11, 2014
CompletedFebruary 11, 2014
February 1, 2014
2.6 years
February 4, 2014
February 9, 2014
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Change (reduction) in the incidence density of Ventilator associated pneumonia (VAP)
Change (reduction) in the incidence density of VAP
Baseline and up to 35 months
Secondary Outcomes (5)
Change(length) in Intensive Care Unit (ICU) stay
Baseline and up to 35 months
Change (number of days) in Mechanical Ventilator (MV) per ICU stay
Baseline and up to 35 months
Change in mortality rate
Baseline and up to 35 months
Change in cost of antimicrobial acquisition during ICU stay
Baseline and up to 35 months
Change in compliance with the measures
Baseline and up to 35 months
Study Arms (1)
bundle implementation
EXPERIMENTALThe measures were a specific training program, aspiration of subglottic secretions (ASS), introduction of an inclinometer to improve the semirecumbent position, and reinforcement of oral care with chlorhexidine.
Interventions
Eligibility Criteria
You may qualify if:
- all patients with heart surgery admitted in critical care unit during the study period
You may not qualify if:
- none
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Maria Jesus Perezlead
- Ciber de Enfermedades Respiratoriascollaborator
- Fundación Rafael del Pinocollaborator
- Fondo de Investigacion Sanitariacollaborator
Study Sites (1)
Hopsital General Universitario Gregorio Marañon
Madrid, Madrid, 28007, Spain
Related Publications (1)
Perez-Granda MJ, Barrio JM, Munoz P, Hortal J, Rincon C, Bouza E. Impact of four sequential measures on the prevention of ventilator-associated pneumonia in cardiac surgery patients. Crit Care. 2014 Mar 26;18(2):R53. doi: 10.1186/cc13799.
PMID: 24667011DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Maria Jesus Perez, RN
Hospital General Universitario Gregorio Marañón
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- RN
Study Record Dates
First Submitted
February 4, 2014
First Posted
February 11, 2014
Study Start
November 1, 2009
Primary Completion
June 1, 2012
Study Completion
June 1, 2012
Last Updated
February 11, 2014
Record last verified: 2014-02