NCT02047396

Brief Summary

To comprehensively characterize Left Ventricular (LV) remodeling after Myocardial Infarction (MI) in the community, study the association between patterns of remodeling and biological pathways and examine the association between the predictors of remodeling and heart failure after Myocardial Infarction.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,599

participants targeted

Target at P75+ for all trials

Timeline
45mo left

Started Jan 2014

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress77%
Jan 2014Jan 2030

Study Start

First participant enrolled

January 1, 2014

Completed
22 days until next milestone

First Submitted

Initial submission to the registry

January 23, 2014

Completed
5 days until next milestone

First Posted

Study publicly available on registry

January 28, 2014

Completed
4.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2018

Completed
11.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2030

Expected
Last Updated

February 23, 2026

Status Verified

February 1, 2026

Enrollment Period

4.7 years

First QC Date

January 23, 2014

Last Update Submit

February 19, 2026

Conditions

Heart FailureMyocardial Infarction

Outcome Measures

Primary Outcomes (1)

  • Heart Failure

    Development of Heart Failure post Myocardial Infarction

    5 years

Secondary Outcomes (1)

  • Death

    5 years

Study Arms (1)

Myocardial Infarction subjects

Subjects with first Myocardial Infarction presenting to one of the Mayo Clinic Hospitals in Rochester, Minnesota.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Subjects in the 7 County area who are admitted to the Mayo Clinic Hospitals in Rochester, Minnesota who have their first myocardial infarction and are willing to have blood drawn and return for an echocardiogram in 3 months.

You may qualify if:

  • Hospitalized patients with a clinical diagnosis of Myocardial Infarction.
  • Residents of Olmsted, Dodge, Goodhue, Wabasha, Winona, Fillmore and Mower Counties.
  • Able to provide informed consent.

You may not qualify if:

  • Previous clinical diagnosis of Myocardial Infarction
  • Previous diagnosis of Heart Failure and/or Cardiomyopathy
  • Diagnosis of Apical Ballooning Syndrome
  • Planned Coronary Artery Bypass Graft (CABG) during index hospitalization
  • Unable to provide informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mayo Clinic

Rochester, Minnesota, 55905, United States

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

Plasma, serum, and WBCs

MeSH Terms

Conditions

Heart FailureMyocardial Infarction

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesMyocardial IschemiaVascular DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosis

Study Officials

  • Suzette Bielinski, PhD

    Mayo Clinic

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
ECOLOGIC OR COMMUNITY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

January 23, 2014

First Posted

January 28, 2014

Study Start

January 1, 2014

Primary Completion

August 31, 2018

Study Completion (Estimated)

January 1, 2030

Last Updated

February 23, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

Locations

US(1)