NCT02042209

Brief Summary

Thoracic pain is the main symptom of acute coronary syndrome (ACS), urgent and serious illness. Whereas hospital mortality decreased until reaching 10%, out-of-hospital mortality remains high: half of the deaths occur during the first two hours. The benefit of an early diagnosis of ACS in term of morbidity and mortality is well established. Identification of the coronary origin of a thoracic pain by the telephone triage physician of the pre-hospital emergency service (SAMU) leads to the sending of a physician staffed ambulance (UMH) and is thus a key element of the prognosis. The aim of the study is to build a telephone predictive score of ACS at the triage of calls for non traumatic thoracic pain. The separate analysis of the questionnaires by sex will authorize the validation of a unique score or two distinct scores for men and women.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,205

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2010

Typical duration for all trials

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2010

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2011

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2012

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

January 17, 2014

Completed
5 days until next milestone

First Posted

Study publicly available on registry

January 22, 2014

Completed
Last Updated

July 29, 2020

Status Verified

July 1, 2020

Enrollment Period

1.6 years

First QC Date

January 17, 2014

Last Update Submit

July 28, 2020

Conditions

Keywords

acute coronary syndromethoracic painprehospitaldiagnostic score

Outcome Measures

Primary Outcomes (1)

  • diagnosis of acute coronary syndrome (ACS)

    The criterion selected to build these scores will be the effective existence of an ACS among included patients.

    one month

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients over 18 years, with a non-traumatic chest pain.

You may qualify if:

  • Patient presenting a non-traumatic chest pain.
  • Call to the telephone triage center in first (direct call from the patient) or second intention (call of another person before the patient)

You may not qualify if:

  • \- Inability to speak directly to the patient

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Bordeaux Hospital Center

Bordeaux, 33000, France

Location

La Réunion Hospital center

Saint-Denis, 97405, France

Location

Toulouse Hosital Center

Toulouse, 31000, France

Location

Related Publications (1)

  • Reuter PG, Pradeau C, Huo Yung Kai S, Lhermusier T, Bourde A, Tentillier E, Combes X, Bongard V, Ducasse JL, Charpentier S. Predicting acute coronary syndrome in males and females with chest pain who call an emergency medical communication centre. Scand J Trauma Resusc Emerg Med. 2019 Oct 17;27(1):92. doi: 10.1186/s13049-019-0670-y.

MeSH Terms

Conditions

Acute Coronary SyndromeChest Pain

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Jean-Louis DUCASSE, PH, MD

    Toulouse Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 17, 2014

First Posted

January 22, 2014

Study Start

May 1, 2010

Primary Completion

December 1, 2011

Study Completion

December 1, 2012

Last Updated

July 29, 2020

Record last verified: 2020-07

Locations