Multi-dimensional Prevention Program After Acute Coronary Syndrome (ELIPS) (SPUM-ACS- SP1)

NCT01075867 | Completed

• 1 other identifier: SPUM-ACS-SP1
• Study Type: observational
• Target: 2,498
• Locations: 1 country
• Sites: 4

Brief Summary

To demonstrate the effectiveness of the ELIPS programme (Multi-dimEnsionaL preventIon Program after Acute coronary Syndrome), which aims at improving quality of care of patients admitted to hospital with Acute Coronary Syndrome (ACS) in the Swiss setting. The program targets an increase in prescription rates by physicians and long term medication adherence and adoption of healthy lifestyle attitudes by patients. The program is dedicated to caregivers to increase their application of guidelines into practice, to increase their confidence in therapeutic education of patients, and to patients to improve their understanding of ACS and its treatment and to increase their motivation for long term treatment,.

Conditions

Acute Coronary Syndrome

Outcome Measures

Primary Outcomes (1)

• composite of death and cardiovascular event

  Composite of * death from any cause, * myocardial infarction, * documented unstable angina requiring rehospitalization, * revascularization (performed at least 30 days after randomization), * documented new or worsen lower limb ischemia, * stroke * transient cerebral ischemic accident.

  1 year

Secondary Outcomes (3)

• Process outcome at discharge

  1 year

• Clinical outcomes at follow-up

  1 year

• Surrogate outcomes at follow-up

  1 year

Study Arms (2)

Control group

Before ELIPS implementation 12 months follow-up

Treatment group

After ELIPS implementation 12 months follow-up

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients Admitted for an Acute Coronary Syndrome

You may qualify if:

• Patients \>18 years
• Admitted for an ACS, that is with symptoms compatible with angina pectoris (chest pain, breathlessness) and at least one of the following 3 features : a) Elevation or depression of the ST segment, inverted T waves or dynamic changes in the repolarization phase b) Positive troponin c) Known coronary artery disease. A significant coronary artery disease must be confirmed angiographically.

You may not qualify if:

• Severe physical disability or dement
• Less than 1 year of life expectancy for non cardiac reason

Sponsors & Collaborators

• University Hospital, Geneva: lead

Study Sites (4)

University Hospital

Bern, Switzerland

Location

University Hospitals

Geneva, Switzerland

Location

University Hospital

Lausanne, Switzerland

Location

University Hospital,

Zurich, Switzerland

Location

Related Publications (1)

• Weidmann L, Obeid S, Mach F, Shahin M, Yousif N, Denegri A, Muller O, Raber L, Matter CM, Luscher TF. Pre-existing treatment with aspirin or statins influences clinical presentation, infarct size and inflammation in patients with de novo acute coronary syndromes. Int J Cardiol. 2019 Jan 15;275:171-178. doi: 10.1016/j.ijcard.2018.10.050. Epub 2018 Oct 16.

  PMID: 30344063 DERIVED

Related Links

• Related Info
• Related Info

MeSH Terms

Conditions

Acute Coronary Syndrome

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Pr

Study Record Dates

• First Submitted: February 24, 2010
• First Posted: February 25, 2010
• Study Start: April 1, 2010
• Primary Completion: December 1, 2013
• Study Completion: December 1, 2018
• Last Updated: April 30, 2020

Record last verified: 2020-04

Locations

CH (4)