Effect of Resistance Training on Musculoskeletal Endocrine Interactions
COMB
Communications of Muscle and Bone
COMB
Communications of Muscle and Bone
Sponsor study identifier
interventional
16
1 country
1
Study Start
October 2013
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
September 2014
Actual (reported)Study Completion
September 2014
Actual (reported)This project will evaluate the impact of resistance training on the synthesis and release of hormones and growth factors from the musculoskeletal system and the extent to which the communicative capacity influences glucose homeostasis In turn, the contribution of glucose regulation on the musculoskeletal system will also be evaluated. This small study will serve as a pilot/feasibility study to define a protocol for implementation of a resistance training intervention in the pediatric population. To establish feasibility, this study population is limited to overweight African American boys ages 7-11 years. In light of well-established accolades of resistance training, historical recommendations for avoidance among the pediatric population have deterred implementation of resistance training interventions in young adolescents. However, contemporary data indicating a profound benefit of resistance training to the skeletal system in pre-adolescents has led to the Academy of Sports Medicine, as well as various other pediatric health interest groups, to support supervised programs incorporating resistance training in young children, emphasizing large muscle and core strengthening. To date, such trials have not been conducted in the pediatric population
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
September 2014
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 2013
Date type not reportedThis date has not been verified as actual or estimated.
December 10, 2013
Actual (reported)January 20, 2014
Actual (reported)September 2014
Actual (reported)September 2014
Actual (reported)Fasting plasma FGF-23 concentration
Fibroblast Growth Factor-23
0,8,12,16, 24 weeks
Fasting serum osteocalcin concentration
0, 8, 12, 16, 24 weeks
Fasting serum insulin concentration
0, 8, 12, 16, 24 weeks
Fasting serum glucose concentration
0, 8, 12, 16, 24 weeks
Bone mineral content
0, 12, 24 weeks
Muscle strength
0, 8, 12, 16, 24 weeks
Muscle density
0, 12, 24 weeks
Bone stress-strain index
0, 12, 24 weeks
Resting energy expenditure
0, 12, 24 weeks
Total fat mass
0, 12, 24 weeks
Total lean mass
0, 12, 24 weeks
No Participation in Resistance Training
Participation in Resistance Training
Supervised strength training 3 days per week for 24 weeks
No supervised strength training throughout the study
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
Hanks LJ, Gutierrez OM, Ashraf AP, Casazza K. Bone Mineral Content as a Driver of Energy Expenditure in Prepubertal and Early Pubertal Boys. J Pediatr. 2015 Jun;166(6):1397-403. doi: 10.1016/j.jpeds.2015.02.054. Epub 2015 Apr 1.
Orlando M Gutierrez, MD, MMSc
University of Alabama at Birmingham
Lynae J Hanks, PhD, RD
University of Alabama at Birmingham
Krista Casazza, PhD, RD
University of Alabama at Birmingham
Marcas Bamman, PhD
University of Alabama at Birmingham
16 participants (actual enrollment reported by the registry).
First Submitted
December 10, 2013
First Posted
January 20, 2014
Study Start
October 2013
Date type not reportedThis date has not been verified as actual or estimated.
Resistance Training as an Aid to Smoking Cessation Treatment
Contact the study team to confirm eligibility.
Ambika Ashraf, MD
University of Alabama at Birmingham
Primary Completion
September 2014
Actual (reported)Study Completion
September 2014
Actual (reported)Last Updated
April 17, 2015
Record last verified: 2015-04
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: