NCT02035722

Brief Summary

Intravitreal injection of Ranibizumab (Lucentis, Genentech) is clinically indicated for patients with wet age-related macular degeneration (AMD) An disadvantage of this technique is the anxiety and discomfort which patients often experience due to the idea of "getting a needle in the eye". In addition, a recent case study indicated the importance of patient education in achieving positive outcomes from intravitreal injections of anti-vascular endothelial growth factor (VEGF) agents. The purpose of our study is to determine whether visual education on AMD and intravitreal injection can reduce patients' anxiety prior to the treatment, and lessen the impact of socioeconomical status on their understanding of the treatment and prognosis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
73

participants targeted

Target at P50-P75 for phase_2

Timeline
Completed

Started Sep 2011

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2011

Completed
2.4 years until next milestone

First Submitted

Initial submission to the registry

January 10, 2014

Completed
4 days until next milestone

First Posted

Study publicly available on registry

January 14, 2014

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2014

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2014

Completed
Last Updated

February 24, 2015

Status Verified

February 1, 2015

Enrollment Period

2.6 years

First QC Date

January 10, 2014

Last Update Submit

February 20, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Anxiety

    Cross-sectional study, where questionnaires will be completed on the same day of clinic visit.

Secondary Outcomes (1)

  • Knowledge of AMD

    Cross-sectional study, where questionnaires will be completed on the same day of clinic visit.

Study Arms (3)

Control group

NO INTERVENTION

AMD-related information is not given to patients randomized to the control group.

Video materials

ACTIVE COMPARATOR

Educational materials are presented in through a video (audio and visual)

Behavioral: Video

Print materials

ACTIVE COMPARATOR

Educational materials are presented in the format of printed brochure (visual)

Behavioral: Printed materials

Interventions

AMD-related information is presented to patients in the form of a brochure (i.e. printed materials)

Print materials
VideoBEHAVIORAL

AMD-related information is presented as in the form of a video

Video materials

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years and older
  • AMD patients requiring intravitreal injections

You may not qualify if:

  • Unable to read or comprehend English
  • Any contraindications to intravitreal injections, such as IOP elevations

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Toronto Western Hospital

Toronto, Ontario, M5T 2S8, Canada

Location

MeSH Terms

Conditions

Macular Degeneration

Interventions

Videotape Recording

Condition Hierarchy (Ancestors)

Retinal DegenerationRetinal DiseasesEye Diseases

Intervention Hierarchy (Ancestors)

Tape RecordingAudiovisual AidsEducational TechnologyTechnologyTechnology, Industry, and AgricultureTelevision

Study Officials

  • Wai-Ching Lam

    University Health Network, Toronto

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 10, 2014

First Posted

January 14, 2014

Study Start

September 1, 2011

Primary Completion

April 1, 2014

Study Completion

June 1, 2014

Last Updated

February 24, 2015

Record last verified: 2015-02

Locations