Marijuana Treatment Project 4
MTP4
Individualized Assessment and Treatment for Marijuana Dependence: Treatment Mechanisms
2 other identifiers
interventional
198
1 country
1
Brief Summary
Marijuana is the most commonly used illicit drug in the US, but treatment for marijuana dependence is not fully effective. In the current proposal we are exploring the idea that more tailored teaching of coping skills may result in improved outcomes for marijuana-dependence than those seen thus far. Participants will be 275 men and women meeting criteria for marijuana dependence and randomly assigned to 9 sessions of treatment in one of 4 treatment conditions: Standardized MET plus CB (SMET-CB); SMET+ CM (SMET-CB-CM); IATP; or IATP + CM (IATP-CM). Patients in all treatments will engage in ES via cell-phone for two weeks prior to treatment, for a weekly period during treatment, for another week after treatment has ended, and for two weekly periods at months 8 and 14. In the IATP conditions, the information gathered from the pretreatment and during-treatment ES periods will provide data for a functional analysis of patients' drug use and urges to use. It is hypothesized that IATP conditions will yield significantly better coping skills acquisition than SMET-CB conditions, both at posttreatment and at extended follow-ups, and that change in coping skills will predict better outcomes for the IATP conditions
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Feb 2013
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2013
CompletedFirst Submitted
Initial submission to the registry
January 7, 2014
CompletedFirst Posted
Study publicly available on registry
January 8, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2018
CompletedJune 21, 2019
June 1, 2019
5.2 years
January 7, 2014
June 19, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Marijuana Use
Marijuana use measured in terms of Days of use in every 90-day period
every 3 months
Secondary Outcomes (1)
Coping Skills
every 3 months
Study Arms (4)
Standardized MET plus CB (SMET-CB)
ACTIVE COMPARATORMotivational Enhancement plus Cognitive-Behavioral treatment
SMET+ CM (SMET-CB-CM)
EXPERIMENTALMotivational Enhancement plus CB treatment plus contingency management
Individualized Assessment & Treatment (IATP)
EXPERIMENTALIndividualized Assessment and Treatment Program; Cognitive-Behavioral Treatment based on in-depth field monitoring of patient behavior
IATP + CM (IATP-CM).
EXPERIMENTALIndividualized Assessment and Treatment plus Contingency Management
Interventions
Reinforcement provided contingent upon demonstration of negative drug tests
Tailored Cognitive-Behavioral Treatment based on detailed records of patient behavior
Standard psychoeducational approach to coping skills training
Eligibility Criteria
You may qualify if:
- at least 18 yrs old
- meet Diagnostic and Statistical Manual IV (DSM-IV) criteria for Cannabis Dependence
- be willing to accept random assignment to any of the 4 treatment conditions
You may not qualify if:
- acute medical/psychiatric problems that require inpatient treatment (e.g., acute psychosis, severe depression, suicide/homicide risk)
- reading ability below the fifth grade level
- lack of reliable transportation
- excessive commuting distance.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- UConn Healthlead
- National Institute on Drug Abuse (NIDA)collaborator
Study Sites (1)
University of Connecticut Health Center
Farmington, Connecticut, 06030, United States
Related Publications (2)
Litt MD, Kadden RM, Tennen H, Dunn HK. Momentary coping and marijuana use in treated adults: Exploring mechanisms of treatment. J Consult Clin Psychol. 2021 Apr;89(4):264-276. doi: 10.1037/ccp0000633.
PMID: 34014689DERIVEDLitt MD, Kadden RM, Tennen H, Petry NM. Individualized assessment and treatment program (IATP) for cannabis use disorder: Randomized controlled trial with and without contingency management. Psychol Addict Behav. 2020 Feb;34(1):40-51. doi: 10.1037/adb0000491. Epub 2019 Jul 18.
PMID: 31318225DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Mark D Litt, PhD
UConn Health
- STUDY DIRECTOR
Elise Kabela-Cormier, PhD
UConn Health
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- FACTORIAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
January 7, 2014
First Posted
January 8, 2014
Study Start
February 1, 2013
Primary Completion
April 1, 2018
Study Completion
April 1, 2018
Last Updated
June 21, 2019
Record last verified: 2019-06