The Effects of Continuous Passive Motion on Hypertonia of Soleus in Individuals With Cerebral Palsy

NCT02003755 | Completed DMC

• 1 other identifier: 99-3614B
• Study Type: interventional
• Target: 8
• Locations: 1 country
• Sites: 1

Brief Summary

Cerebral palsy (CP) is a group of disorders of the development of movement and posture but often changing motor impairment syndromes. The spastic subtypes are the most common manifestations of cerebral palsy who perform movement difficultly due to hypertonia. Decease of spinal cord pathway, hyperactivity of alpha and gamma motoneuron and reduction of presynaptic inhibition may cause tendon reflex increase and hypertonia in individuals with CP. There are many ways to improve the hypertonia. In the past studies, the fast repeated range of motion could reduce muscle's activation effectively. The polyarticular movement training might increase joint range of motion and reduce the muscle activation. But the polyarticular movement training is difficulty for some individuals with CP. The single joint movement training may achieve the same effect as the polyarticular movement training. The purpose of this study was to investigate the effects of continuation passive range of motion (CPM) training whether could get the improvement of soleus hypertonia in individuals with CP.

Conditions

Cerebral Palsy (CP)

Keywords

Cerebral palsy; Continuous passive motion; Hypertonia

Outcome Measures

Primary Outcomes (3)

• Muscle tone tests

  Measure of changes in Hypertonia measured by Modified Ashworth Scale (MAS).

  Baseline, 1, and 4 months.

• Ankle range of motion

  Measure of changes in Ankle range of motion.

  Baseline, 1, and 4 months.

• Hoffman reflex (H-reflex)

  Measure of changes in Hoffman reflex (H-reflex).

  Baseline, 1, and 4 months.

Secondary Outcomes (1)

• Leg girth

  Baseline,1 ,and 4 mouths.

Study Arms (1)

Spastic CP

EXPERIMENTAL

continuous passive motion training

Procedure: Ankle continuous passive motion machine.

Interventions

Ankle continuous passive motion machine. PROCEDURE

A rehabilitation program of machine driven passive stretch.

Spastic CP

Eligibility Criteria

• Age: 16 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Clinical diagnosis of Spastic CP
• Modified Ashworth scale of Soleus \> 1
• Ankle range of motion \> 10 degrees

You may not qualify if:

• Fracture on lower Lower extremities
• BOTOX on ankle \< 5 mouths

Sponsors & Collaborators

• Chang Gung University: lead

Study Sites (1)

Chang Gung University

Taoyuan District, 333, Taiwan

Location

MeSH Terms

Conditions

Cerebral Palsy; Muscle Hypertonia

Condition Hierarchy (Ancestors)

Brain Damage, Chronic; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neuromuscular Manifestations; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: December 3, 2013
• First Posted: December 6, 2013
• Study Start: April 1, 2011
• Primary Completion: April 1, 2013
• Study Completion: April 1, 2013
• Last Updated: December 6, 2013

Record last verified: 2013-12

Locations

TW (1)