Prevalence and Outcome of Hypermetabolism in Initial Prevalence and Outcome of Hypermetabolism in Initial Phase of Intensive Care Unit Patient: a Prospective Observational Study
1 other identifier
observational
62
1 country
1
Brief Summary
Patients in critical illness frequently present hypermetabolism， which can extremely increase the rest energy expenditure（REE）. We hypothesize that if we alleviate the extremely increased REE will improve ICU patients' outcome
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Dec 2013
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 26, 2013
CompletedStudy Start
First participant enrolled
December 1, 2013
CompletedFirst Posted
Study publicly available on registry
December 6, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2014
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2014
CompletedJune 13, 2014
June 1, 2014
6 months
November 26, 2013
June 12, 2014
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Mortality rate of 28 days
From ICU admission to 28th days of observation
Secondary Outcomes (1)
Incidence of Multiple Organ Dysfunction Syndrome（MODS）in 60 days
From ICU admission to 60th days of observation
Other Outcomes (1)
Length of stay in ICU
Length of ICU stay within 60 days
Eligibility Criteria
Patients who admitted ICU with hypermatebolic status, which the results of indirect calorimetry show that the actual rest energy expenditure values are remarkably higher than the predicted ones.
You may qualify if:
- Older than 18 year.
- APACHEⅡ score≥8
You may not qualify if:
- Hypercortisolism
- Thyroid disease
- Tracheoesophageal fistula
- FiO2\>60 or PEEP\>12cm H2O in mechanical ventilate
- Pregnancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Nanjing University School of Medicinelead
- Jinling Hospital, Chinacollaborator
Study Sites (1)
Nanjing University School of Medicine
Nanjing, Jiangsu, 210093, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Xinying Wang, MD
Nanjing University School of Medicine
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Ph.D.candidate
Study Record Dates
First Submitted
November 26, 2013
First Posted
December 6, 2013
Study Start
December 1, 2013
Primary Completion
June 1, 2014
Study Completion
June 1, 2014
Last Updated
June 13, 2014
Record last verified: 2014-06