Suicidal Thought and Biological Markers

NCT01992445 | Completed

• 1 other identifier: 20133770
• Study Type: observational
• Target: 375
• Locations: 1 country
• Sites: 3

Brief Summary

Thought Markers (Tm) and Biomarkers(Bm) to accurately predict the likelihood of a repeated suicide attempt.

Conditions

Suicidal Intention

Keywords

suicide; suicidal intent; thought markers

Outcome Measures

Primary Outcomes (1)

• Columbia Suicide Severity Rating Scale

  Questionnaire

  1 month

Secondary Outcomes (3)

• Acoustic analysis of voice

  1 month

• Video analysis

  Baseline

• DNA analysis

  Baseline

Study Arms (3)

Suicidal

Other mental health

Control (non suicidal, non mental health)

Eligibility Criteria

• Age: 13 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Emergency Department and inpatients

You may qualify if:

• oBe able to understand the requirements of the study and provide written informed consent to participate in this study. Signed and dated informed consent will be obtained from each patient before participation in the study, oHave provided written authorization for the use and disclosure of their protected health information, oBe 13 years of age or older, oBe diagnosed with: oSuicide ideation/attempts/gestures, or oNon-suicidal and having other mental disorders, oNon-mentally ill, and non-suicidal controls, oSpeak English as the primary language in the home, oAgree to abide by the study protocol and its restrictions and be able to complete all aspects of the study.

You may not qualify if:

• oSignificant unstable medical condition that may obscure the scientific interpretability of the study or unduly increase the risks of the protocol, oAnticipated inability to attend follow-up phone interview, oPatients whose level of consciousness precludes consent and research assessments, oPatients unable to assent because of severe mental retardation, oPatients who in the judgment of the Investigator may be unreliable or uncooperative with the evaluation procedure outlined in this protocol, oFor control patients a diagnosis of depression or another non-mental illness, or a history of suicidal behavior or suicidal attempt, oPatients who are unwilling to provide the DNA sample.

Sponsors & Collaborators

• Children's Hospital Medical Center, Cincinnati: lead

Study Sites (3)

CCHMC

Cincinnati, Ohio, 45229, United States

Location

University of Cincinnati

Cincinnati, Ohio, 45267, United States

Location

Princeton Community Hospital

Princeton, West Virginia, 24740, United States

Location

Biospecimen

Retention: SAMPLES WITH DNA

Buccal swabs

MeSH Terms

Conditions

Suicide

Condition Hierarchy (Ancestors)

Self-Injurious Behavior; Behavioral Symptoms; Behavior

Study Officials

• John Pestian, PhD

  CCHMC

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 8, 2013
• First Posted: November 25, 2013
• Study Start: October 1, 2013
• Primary Completion: March 1, 2015
• Study Completion: March 1, 2015
• Last Updated: May 23, 2016

Record last verified: 2016-05

Locations

US (3)