NCT01982058

Brief Summary

RATIONALE: Participating in a therapy program may enhance communication and intimacy between men with prostate cancer and their partners. PURPOSE: This randomized clinical trial is studying how well therapy enhances communication and intimacy for men with early stage prostate cancer and for their partners.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
483

participants targeted

Target at P75+ for not_applicable prostate-cancer

Timeline
Completed

Started Aug 2011

Longer than P75 for not_applicable prostate-cancer

Geographic Reach
1 country

6 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 18, 2011

Completed
1.9 years until next milestone

First Submitted

Initial submission to the registry

June 24, 2013

Completed
5 months until next milestone

First Posted

Study publicly available on registry

November 13, 2013

Completed
3.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 7, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 7, 2017

Completed
Last Updated

October 19, 2022

Status Verified

October 1, 2022

Enrollment Period

6 years

First QC Date

June 24, 2013

Last Update Submit

October 17, 2022

Conditions

Outcome Measures

Primary Outcomes (2)

  • Psychological Functioning

    General psychological functioning is assessed by the MHI-38 and the PHQ-9. Cancer-Specific distress is assessed by using the Impact of Events Scale Revised Cancer-Specific concerns is assessed with a 10 item assessment of commonly-experienced problems.

    5 years

  • Relationship Functioning

    Relationship satisfaction is assessed using the Dyadic Adjustment Scale

    5 years

Secondary Outcomes (2)

  • Intimacy

    5 years

  • Relationship Communication

    5 years

Study Arms (3)

Intimacy-Enhancing Couples

EXPERIMENTAL

Patients and their partners receive communication and intimacy-enhancing intervention (IEC) once a week comprising the following five 90-minute sessions: Orientation and Stories of the Cancer Experience; Communication and Listening to Partner's concerns; Communication and Coping with Cancer Issues as a Team; Being Supportive to Solve Concerns; and Reflecting on Changes and Future Adaptation.

Other: communication interventionOther: counseling interventionOther: questionnaire administration

General Health and Wellness

ACTIVE COMPARATOR

Patients and their partners receive a General Health and Wellness intervention focusing on nutrition and physical activity once a week comprising of five 90-minute sessions: Introduction and Nutrition Basics; Nutrition and Prevention of Recurrence; Nutritional Review and Introduction to Relaxation; Physical Activity Basics; Aerobics and Resistance Exercises and Wrap up.

Other: counseling interventionOther: nutrition interventionOther: questionnaire administration

Usual Care

OTHER

Patients and their partners receive standard psychological and emotional care (usual care \[UC\]) (i.e., social work consultations and referral to a psychiatrist or psychologist, if requested or deemed necessary by the attending physician).

Other: questionnaire administration

Interventions

Intimacy-Enhancing Couples
General Health and WellnessIntimacy-Enhancing Couples
General Health and Wellness
General Health and WellnessIntimacy-Enhancing CouplesUsual Care

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient has a primary diagnosis of localized prostate cancer (T1, T2, N=0 M=0, T3 N=0 M=0)
  • Patient had surgery or initiated radiation treatment (brachytherapy or external beam radiation) or began pre-radiation Androgen deprivation therapy within the past 12 months.
  • Patient is currently married or living with a partner, with relationship duration at least 1 year
  • Patient and partner live within a 1 hour commuting distance to recruitment site
  • Patient and partner read and speak English
  • Patient has an Impact of Events Scale (IES) score greater than or equal to 16 and/or partner has an IES score greater than or equal to 17.

You may not qualify if:

  • Patient had a previous definitive treatment for prostate cancer
  • Patient has a concurrent diagnosis of another cancer (other than non-melanoma skin cancer)
  • Partner is diagnosed with cancer (other than non-melanoma skin cancer)
  • Patient or partner have a significant hearing impairment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, 08903, United States

Location

The University Hospital

Newark, New Jersey, 07103, United States

Location

Garden State Urology

Whippany, New Jersey, 07981, United States

Location

Memorial Sloan-Kettering Cancer Center

New York, New York, 10022, United States

Location

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

Location

Fox Chase Cancer Center

Philadelphia, Pennsylvania, 19111, United States

Location

MeSH Terms

Conditions

Prostatic NeoplasmsSexual Dysfunction, PhysiologicalInfertilitySexuality

Interventions

CounselingDiet Therapy

Condition Hierarchy (Ancestors)

Genital Neoplasms, MaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsGenital Diseases, MaleGenital DiseasesUrogenital DiseasesProstatic DiseasesMale Urogenital DiseasesSexual BehaviorBehavior

Intervention Hierarchy (Ancestors)

Mental Health ServicesBehavioral Disciplines and ActivitiesCommunity Health ServicesHealth ServicesHealth Care Facilities Workforce and ServicesNutrition TherapyTherapeutics

Study Officials

  • Sharon L Manne, Ph.D.

    Rutgers Cancer Institute of New Jersey

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Medicine

Study Record Dates

First Submitted

June 24, 2013

First Posted

November 13, 2013

Study Start

August 18, 2011

Primary Completion

August 7, 2017

Study Completion

August 7, 2017

Last Updated

October 19, 2022

Record last verified: 2022-10

Data Sharing

IPD Sharing
Will not share

Locations