NCT01966965

Brief Summary

This study aims to demonstrate the therapeutic efficacy and safety of Shampoo PIOLIN ® in the treatment of human pediculosis. Will be treated 212 patients aged 2-60 years with the infestation, along with the people in your family life. All will be submitted to the dosing regimen recommended in the package insert. 100% of the sample shall be subjected to clinical evaluation through comb, pre and post treatment and monitored after thirty days for evaluation of safety and possible adverse effects that may arise related to any of the components of the formula. The efficacy study is active comparator, non-inferiority.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
212

participants targeted

Target at P25-P50 for phase_3

Timeline
Completed

Started Jul 2014

Shorter than P25 for phase_3

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 17, 2013

Completed
5 days until next milestone

First Posted

Study publicly available on registry

October 22, 2013

Completed
8 months until next milestone

Study Start

First participant enrolled

July 1, 2014

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2014

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2014

Completed
Last Updated

October 23, 2013

Status Verified

October 1, 2013

Enrollment Period

2 months

First QC Date

October 17, 2013

Last Update Submit

October 22, 2013

Conditions

Keywords

PIOLIN®, PEDICULOSIS, EFFICACY, SAFETY, PHYTOMEDICINE,ARRUDA, RUTA

Outcome Measures

Primary Outcomes (1)

  • EFFICACY

    AFTER 17 DAYS OF TREATMENT PATIENTS SHOULD HAVE NO INFESTATION - clinically

    17 DAYS

Secondary Outcomes (1)

  • SAFETY

    30 DAYS

Study Arms (2)

PIOLIN®

EXPERIMENTAL

PIOLIN® SHAMPOO 5 DAYS CONTINUOUSLY STOP A WEEK AND APPLY AGAIN

Drug: PIOLIN®

NEDAX

ACTIVE COMPARATOR

FOLLOWING THE LEAFLET TREATMENT

Drug: NEDAX

Interventions

PIOLIN® SHAMPOO 5 DAYS CONTINUOUSLY STOP A WEEK AND APPLY AGAIN

Also known as: RUTA GRAVEOLENS STANDARDIZED FLUID EXTRACT
PIOLIN®
NEDAXDRUG

AS SPECIFIED AT THE LEAFLET

Also known as: PERMETRIN
NEDAX

Eligibility Criteria

Age2 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Volunteers healthy female and male ;
  • Children between 2 and 17 years ;
  • Increased from 18 years;
  • Availability of volunteer to maintain a stable weight during the study period (ranging from less than 2 kg) ;
  • Displays lice infestation on clinical examination ;
  • Voluntary participation ;
  • Signing the consent form and / or Free and Informed Consent ;
  • Willingness to comply with study procedures ;
  • Complying that researchers can make use of all the information nameless , including publication and comply with the use and storage of all information confidential .

You may not qualify if:

  • Use paint or other chemicals on the hair in the last four weeks that precede the study ;
  • Concomitant Therapy ;
  • Women who are pregnant or intend to become pregnant during the study ;
  • Infants ;
  • Volunteers not willing to sign and adhere to the Statement of Consent ;
  • Known hypersensitivity to the product ;
  • Participation in any other clinical study ;
  • Any other condition that the investigator decides that might interfere with the results or involving a risk to the volunteer study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ubs Fatima

Pelotas, Rio Grande do Sul, 96075-540, Brazil

Location

Related Links

MeSH Terms

Conditions

Lice Infestations

Condition Hierarchy (Ancestors)

Ectoparasitic InfestationsSkin Diseases, ParasiticParasitic DiseasesInfectionsSkin Diseases, InfectiousSkin DiseasesSkin and Connective Tissue Diseases

Study Officials

  • MONICA M MENDES, MD MSc

    UCPEL-UNIVERSIDADE CATÓLICA DE PELOTAS

    PRINCIPAL INVESTIGATOR
  • ACHILLES GENTILINI NETO, MD

    INDEPENDENT

    STUDY CHAIR

Central Study Contacts

KARLA F DEUD JOSÉ, PharmD PhD

CONTACT

Karla F Deud José, PharmD PhD

CONTACT

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
NETWORK
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
CEO

Study Record Dates

First Submitted

October 17, 2013

First Posted

October 22, 2013

Study Start

July 1, 2014

Primary Completion

September 1, 2014

Study Completion

October 1, 2014

Last Updated

October 23, 2013

Record last verified: 2013-10

Locations