Lactate Use as Triage Tool in Sepsis : Veinous, Capillary or Arterial?
Lactate and Sepsis : What Dosage Use as Triage Tool in Emergency Department for Patients With Suspected Infection.
2 other identifiers
observational
103
1 country
1
Brief Summary
Severe sepsis and septic shocks are increasingly codified. A biomarker as Lactate is very interesting to detect those situations. Usually, lactate used is arterial but results are often too slow to obtain if we want to respect Surviving Sepsis Campaign guidelines. Some analyzers (EKF diagnostics Lactate Scout\*) can give results in 15 seconds. We hypothesized that capillary lactate, easy to sample, tested with this analyzer may detect earlier those infections states and we want to find the most accurate site to detect severe sepsis (capillary, venous or arterial sample).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Dec 2013
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 15, 2013
CompletedFirst Posted
Study publicly available on registry
October 17, 2013
CompletedStudy Start
First participant enrolled
December 1, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2014
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2014
CompletedApril 29, 2014
January 1, 2014
4 months
October 15, 2013
April 26, 2014
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Lactate value
Determine the most accurate value of capillary or venous lactate that may be able to early detect patients with severe sepsis or septic shock, using quick test (EKF diagnostics Lactate scout\*).
At admission in emergency department
Secondary Outcomes (2)
Comparison values of capillary lactate and arterial lactate
30 minutes after sampling
Mortality
Day 28 mortality
Eligibility Criteria
Patients with suspected infection in emergency department (admission time)
You may qualify if:
- Age \>18 years
- S.I.R.S : 2 or more criteria (fever \> 38.3°C or hypothermia (core temperature \< 36°C) heart rate \> 90.min-1, tachypnea, altered mental status)
- Suspected infection
You may not qualify if:
- Arterial sample by laboratory reference method no available
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hopital Saint Roch
Nice, Alpes-maritimes, 06000, France
Related Publications (1)
Contenti J, Corraze H, Lemoel F, Levraut J. Effectiveness of arterial, venous, and capillary blood lactate as a sepsis triage tool in ED patients. Am J Emerg Med. 2015 Feb;33(2):167-72. doi: 10.1016/j.ajem.2014.11.003.
PMID: 25432592DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Contenti Julie, M.D
Association pour la Formation l'Enseignement et la Recherche du Service de l'Accueil des Urgences
- STUDY DIRECTOR
Jacques Levraut, PD,MD
CHU de Nice, France
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- AFERSAU
Study Record Dates
First Submitted
October 15, 2013
First Posted
October 17, 2013
Study Start
December 1, 2013
Primary Completion
April 1, 2014
Study Completion
April 1, 2014
Last Updated
April 29, 2014
Record last verified: 2014-01