Chronic Effects of Two Aerobic-training Models Performed in Water and on Dry Land in Patients With Type 2 Diabetes Mellitus (T2DM).

NCT01956357 | Completed

• 1 other identifier: 54475
• Study Type: interventional
• Target: 35
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to analyse the acute and chronic effects of two aerobic-training models performed in water and on dry land on cardiorespiratory, functional, metabolic, hormonal and quality-of-life parameters in patients with type 2 diabetes mellitus (T2DM).

Conditions

Diabetes Mellitus, Type 2

Keywords

aquatic exercises;; deep water running;; diabetes;; blood glucose;; inflammation.

Outcome Measures

Primary Outcomes (1)

• Glycated hemoglobin

  Baseline and after 12 weeks of intervention

Secondary Outcomes (26)

• Fasting plasma glucose.

  Before and after a session of 45 minutes of exercise; baseline and after 12 weeks of intervention.

• Postprandial glucose

  Baseline and after 12 weeks of intervention.

• Fasting insulin.

  Baseline and after 12 weeks of intervention.

• Insulin resistance (HOMA-IR).

  Baseline and after 12 weeks of intervention.

• Total cholesterol.

  Baseline and after 12 weeks of intervention.

Other Outcomes (10)

• Peak oxygen consumption.

  Baseline and after 12 weeks of intervention.

• Timed up and go in habitual speed and maximal speed.

  Baseline and after 12 weeks of intervention.

• Oxygen uptake at ventilatory threshold.

  Baseline and after 12 weeks of intervention.

Study Arms (2)

Aquatic exercise

EXPERIMENTAL

The aquatic aerobic training had a duration of 12 weeks and adopted the interval-training method, with intensities ranging between 85 and 100% of second ventilatory threshold (VT2) and total duration of 45 minute per session. The sessions consisted of warm up, main part and calm down. The warm-up consisted of a walk in deep water at low intensity for three minutes. The main part was intended to aerobic training in deep water, in which subjects walked and / or ran, depending on your fitness level found in pre-training test. The calm down consisted of walking in deep water at low intensity for two minutes and stretching standardized, emphasizing the muscles worked in the main part of the session, with a total duration of approximately five minutes.

Other: Aquatic exercise

Land exercise

EXPERIMENTAL

The land aerobic training had a duration of 12 weeks and adopted the interval-training method, with intensities ranging between 85 and 100% of second ventilatory threshold (VT2) and total duration of 45 minute per session. The sessions consisted of warm up, main part and calm down. The warm-up consisted of a walk in athletic track at low intensity for three minutes. The main part was intended to aerobic training in athletic track, in which subjects walked and / or ran, depending on your fitness level found in pre-training test. The calm down consisted of walking in athletic track at low intensity for two minutes and stretching standardized, emphasizing the muscles worked in the main part of the session, with a total duration of approximately five minutes.

Other: Land Exercise

Interventions

Aquatic exercise OTHER

Aquatic exercise

Land Exercise OTHER

Land exercise

Eligibility Criteria

• Age: 30 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• The clinical diagnosis of type 2 diabetes mellitus. Not be performing regular and systematic physical exercise for at least three months.

You may not qualify if:

• Uncontrolled hypertension. Autonomic neuropathy. Severe peripheral neuropathy. Proliferative diabetic retinopathy. Severe nonproliferative diabetic retinopathy. Uncompensated heart failure. Peripheral amputations. Chronic renal failure (GFR by MDRD \<30). Muscle or joint injury that prevents physical exercises.

Sponsors & Collaborators

• Hospital de Clinicas de Porto Alegre: lead

Study Sites (1)

Physical Education School of Federal University of Rio Grande do Sul

Porto Alegre, Rio Grande Do Sil, 90690-200, Brazil

Location

Related Publications (2)

• S Delevatti R, Schuch FB, Kanitz AC, Alberton CL, Marson EC, Lisboa SC, Pinho CDF, Bregagnol LP, Becker MT, Kruel LFM. Quality of life and sleep quality are similarly improved after aquatic or dry-land aerobic training in patients with type 2 diabetes: A randomized clinical trial. J Sci Med Sport. 2018 May;21(5):483-488. doi: 10.1016/j.jsams.2017.08.024. Epub 2017 Sep 6.

  PMID: 28935128 DERIVED

• Delevatti RS, Pinho CD, Kanitz AC, Alberton CL, Marson EC, Bregagnol LP, Lisboa SC, Schaan BD, Kruel LF. Glycemic reductions following water- and land-based exercise in patients with type 2 diabetes mellitus. Complement Ther Clin Pract. 2016 Aug;24:73-7. doi: 10.1016/j.ctcp.2016.05.008. Epub 2016 May 10.

  PMID: 27502804 DERIVED

MeSH Terms

Conditions

Diabetes Mellitus, Type 2; Diabetes Mellitus; Inflammation

Interventions

Aquatic Therapy

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Hydrotherapy; Physical Therapy Modalities; Therapeutics; Rehabilitation

Study Officials

• Rodrigo S Delevatti, MSc

  Hospital de Clínicas de Porto Alegre

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Effects of two models of aerobic training performed in different environments in patients with type 2 diabetes mellitus

Study Record Dates

• First Submitted: September 27, 2013
• First Posted: October 8, 2013
• Study Start: August 1, 2012
• Primary Completion: December 1, 2012
• Last Updated: November 5, 2014

Record last verified: 2014-05

Locations

BR (1)