NCT01955850

Brief Summary

The object of this study is to compare internet-delivered treatment for insomnia to face-to-face treatment and a waiting-list. In this study participants are randomized to: 1) online cognitive-behavioral intervention; 2) face-to-face cognitive behavioral intervention; 3) waiting-list. Both the online and face-to-face interventions consist of: diary; psycho-education; relaxation exercises; stimulus control/sleep hygiene; sleep restriction; challenging the misconceptions about sleep; and paradoxical exercise. Adult persons with insomnia will be invited via a popular scientific website to fill out online questionnaires. Participants fill out questionnaires and a dairy at baseline post-test, 3-month follow-up, and 6-month follow-up. Participants on the waiting-list receive online treatment after the first post-test. The investigators expect that the online-delivered treatment and the face-to-face treatment are equally effective.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
90

participants targeted

Target at below P25 for phase_3

Timeline
Completed

Started Oct 2013

Shorter than P25 for phase_3

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 20, 2013

Completed
11 days until next milestone

Study Start

First participant enrolled

October 1, 2013

Completed
7 days until next milestone

First Posted

Study publicly available on registry

October 8, 2013

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2014

Completed
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2014

Completed
Last Updated

December 30, 2014

Status Verified

December 1, 2014

Enrollment Period

6 months

First QC Date

September 20, 2013

Last Update Submit

December 29, 2014

Conditions

Outcome Measures

Primary Outcomes (2)

  • Sleep continuity (consisting of sleep latency, time awake after sleep onset, total sleep time)

    For sleep continuity a 7-day sleep diary is used based on the consensus sleep diary.

    Change from baseline to post-test, 3-months, and 6-months follow-up

  • Insomnia Severity Index

    Change from baseline to post-test, 3-months, and 6-months follow-up

Secondary Outcomes (6)

  • Anxiety (HADS-A)

    Change from baseline to post-test, 3-months, and 6-months follow-up

  • Sleep related worry measured with the Anxiety and Pre-occupation about Sleep Scale

    Change from baseline to post-test, 3-months, and 6-months follow-up

  • Sleep related arousal measured with the Pre-arousal sleep scale

    Change from baseline to post-test, 3-months, and 6-months follow-up

  • Sleep related cognitions measured with the Dysfunctional Beliefs and Attitudes about sleep scale (DBAS)

    Change from baseline to post-test, 3-months, and 6-months follow-up

  • Sleep medication usage per day measured with the sleep diary

    Change from baseline to post-test, 3-months, and 6-months follow-up

  • +1 more secondary outcomes

Study Arms (3)

Internet-delivered CBT for insomnia

EXPERIMENTAL

Online Cognitive behavioral treatment for insomnia

Behavioral: Cognitive behavioral treatment for insomnia

Face-to-face CBT for insomnia

EXPERIMENTAL

Face-to-face Cognitive behavioral treatment for insomnia

Behavioral: Cognitive behavioral treatment for insomnia

Waiting-list

NO INTERVENTION

Waiting-list

Interventions

Cognitive behavioral treatment for insomnia, consisting of: psycho-education, sleep hygiene, stimulus control, sleep restriction, cognitive therapy.

Face-to-face CBT for insomniaInternet-delivered CBT for insomnia

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Insomnia disorder according to DSM-5
  • Sleep onset latency/wake after sleep onset \> 30 minutes , three times or more a week
  • Insomnia three months or longer
  • Access to internet
  • Possibility to travel to one of the treatment sites

You may not qualify if:

  • Earlier cognitive behavioral treatment for insomnia
  • Start other psychological treatment in the last 6 months
  • Doing shift work
  • Major depression disorder
  • Pregnancy or breast feeding
  • Schizophrenia or psychosis
  • Suicidal plans
  • Sleep apnea
  • drugs or alcohol abuse

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Clinical Psychology

Amsterdam, North Holland, 1018XA, Netherlands

Location

Related Publications (2)

  • Lancee J, van den Bout J, van Straten A, Spoormaker VI. Internet-delivered or mailed self-help treatment for insomnia?: a randomized waiting-list controlled trial. Behav Res Ther. 2012 Jan;50(1):22-9. doi: 10.1016/j.brat.2011.09.012. Epub 2011 Oct 24.

    PMID: 22055281BACKGROUND
  • Lancee J, van Straten A, Morina N, Kaldo V, Kamphuis JH. Guided Online or Face-to-Face Cognitive Behavioral Treatment for Insomnia: A Randomized Wait-List Controlled Trial. Sleep. 2016 Jan 1;39(1):183-91. doi: 10.5665/sleep.5344.

Related Links

MeSH Terms

Conditions

Sleep Initiation and Maintenance Disorders

Condition Hierarchy (Ancestors)

Sleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System DiseasesMental Disorders

Study Officials

  • Jaap Lancee, PhD

    University of Amsterdam

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PhD

Study Record Dates

First Submitted

September 20, 2013

First Posted

October 8, 2013

Study Start

October 1, 2013

Primary Completion

April 1, 2014

Study Completion

December 1, 2014

Last Updated

December 30, 2014

Record last verified: 2014-12

Locations