NCT01952496

Brief Summary

The goal of this project is to design and validate a force-measuring platform that will measure the magnitude and duration of the load experienced by the lower extremities of individuals with a neuromuscular disability who use a stationary assisted standing device to increase their Bone Mineral Density.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2014

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 17, 2013

Completed
13 days until next milestone

First Posted

Study publicly available on registry

September 30, 2013

Completed
4 months until next milestone

Study Start

First participant enrolled

February 1, 2014

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2015

Completed
Last Updated

February 17, 2016

Status Verified

February 1, 2016

Enrollment Period

1.6 years

First QC Date

September 17, 2013

Last Update Submit

February 15, 2016

Conditions

Keywords

Cerebral PalsyNon ambulatoryNeuromuscular disabilityChildren

Outcome Measures

Primary Outcomes (1)

  • Bone Mineral Density

    Bone Mineral Density will be measured via dual energy x-ray absorptiometry (DXA) and peripheral quantitative computed tomography (pQCT) scans.

    12 months

Secondary Outcomes (3)

  • Weight (load)experienced by lower extremities

    12 months

  • Duration of standing treatment session(s) (time)

    12 months

  • Caregiver Priorities & Child Health Index of Life with Disabilities (CPCHILD) questionnaire

    12 months

Study Arms (1)

Force-measuring platform

OTHER

A force-measure platform will be placed under each foot of the subject to record the time course of load borne by each of the lower extremities during weight-bearing training in an assisted standing device. Intervention: Assisted Standing Treatment Program. Assisted standing treatment program will include at least 2 hours a day, 5 days a week (a total of at least 10 hours a week) for a period of \~9 months.

Other: Assisted Standing Treatment Program

Interventions

Assisted standing treatment program will include at least 2 hours a day, 5 days a week (a total of at least 10 hours a week) for a period of \~9 months. Arm: Force-measuring platform

Force-measuring platform

Eligibility Criteria

AgeUp to 17 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • \< 18 years old
  • Diagnosed with Cerebral Palsy (CP)
  • Treated at Gillette Children's Specialty Healthcare
  • Gross Motor Function Classification System level of IV or V (non-ambulatory without assistance)
  • Participating in a standing program using a stationary assisted standing device
  • Parent/Guardian willing and able to give consent

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Clinical and Translational Science Institute at University of Minnesota

Minneapolis, Minnesota, 55414, United States

Location

Gillette Children's Specialty Healthcare

Saint Paul, Minnesota, 55101, United States

Location

MeSH Terms

Conditions

Cerebral Palsy

Condition Hierarchy (Ancestors)

Brain Damage, ChronicBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Study Officials

  • Walter Truong, MD

    Gillette Children's Specialty Healthcare

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 17, 2013

First Posted

September 30, 2013

Study Start

February 1, 2014

Primary Completion

September 1, 2015

Study Completion

September 1, 2015

Last Updated

February 17, 2016

Record last verified: 2016-02

Locations