NCT01950962

Completed

Role Of Phospholipid Transfer Proteins (Pltp) On Endotoxemia...

Centre Hospitalier Universitaire Dijon Source

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Other study identifiers

Sponsor study identifier

Lafon PHRC IR 2010

Study Type

interventional

Actual enrollment (reported)

242

Locations

1 country

Sites

1

Timeline

Study Start

October 14, 2010

Actual (reported)

Primary Completion

June 12, 2014

Actual (reported)

Study Completion

Not reported

Date not reported

Brief Summary

This is a transversal double-centre study. Patients will be recruited from outpatient consultations. They will have buccal inflammation caused by periodontal disease (frequent oral infections, mostly with GRAM (-) bacteria). Three groups of 80 patients, corresponding to slight, moderate and severe periodontal disease, will be formed according to the results of radiological and clinical examinations.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Actual enrollment (reported): 242 participants
Study completion date: Not reported
Date not reported
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Some registry-reported names shown below are not yet linked in this graph.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
October 14, 2010
Actual (reported)
First Submitted
August 27, 2013
Actual (reported)
First Posted
September 26, 2013
Actual (reported)
Primary Completion
June 12, 2014
Actual (reported)

Last Updated: July 30, 2019
Status Verified: July 2019
Last Update Submitted: July 26, 2019

Conditions

Patients With Periodontal Disease

Outcome Measures

Primary Outcomes (1)

Score of severity of oral inflammation
up to 5 days

Study Arms (3)

slight periodontal disease

OTHER

Other: Sampling of blood

moderate periodontal disease

OTHER

Other: Sampling of blood

severe periodontal disease

OTHER

Other: Sampling of blood

Interventions

Sampling of bloodOther

moderate periodontal diseasesevere periodontal diseaseslight periodontal disease

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age35 Years - 80 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Persons aged from 35 to 80 years old
Persons who have provided written informed consent

Sponsors & Collaborators

Centre Hospitalier Universitaire Dijon
Otherlead

Study Sites (1)

CHU Dijon

Dijon, 21000, France

Enrollment

242 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NON RANDOMIZED
Masking: NONE
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

August 27, 2013

First Posted

September 26, 2013

Study Start

October 14, 2010

Actual (reported)

Unknown

NCT01962129

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Unknown

NCT01931800

Identification and Quantification of Immune Response Induced by Hyaluronidase and Other Factors of Virulence of Invasive Human Infections of Streptococcus Pneumoniae

Completed

Patients with periodontal disease whatever the severity with at least one molar or one premolar on the dental arch

Possibility to examine the oral cavity (patient able to open mouth)

Possibility to do an orthopantomogram (sitting position required and patient able to clench jaws)

Patient able to understand French

Patient who accepts to provide fasting blood sample within the five days following the initial consultation

\- Patient present for the fasting blood sample within five days following the initial consultation Patients will be matched for sex and, as much as possible, for age in the three groups and for the severity of the periodontal disease

You may not qualify if:

Persons not covered by the national health insurance agency
Patients with a high risk of infectious endocarditis who require prophylaxis for any medical act involving blood
Patients who have had long-term treatment (\>6 months) with corticoids at a dose of at least 15 mg per day
Patients on antibiotics less than 15 days before the blood sample
Scaling during the 24 hours before the blood sample
History of oral cancer or cancer of the pharynx
Active cancer (patient undergoing treatment or diagnosis within the previous 5 years)
Iatrogenic, spontaneous or therapeutic immunodepression (patient on immunosuppressants or antiretrovirals),
Systemic or organ specific inflammatory syndrome not related to the periodontal disease
proven bacterial, viral or fungal Infection either developing or being treated (urinary, prostate infection)
Inflammatory cancer (solid tumour, malignant hemopathy)
Pregnancy
Impossibility to cooperate due to a psychiatric disease, dementia
Patients unable to understand the protocol

Contact the study team to confirm eligibility.

Primary Completion

June 12, 2014

Actual (reported)

Last Updated

July 30, 2019

Record last verified: 2019-07

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT01950962
Data provider: ClinicalTrials.gov
Source updated: 2019-07-30
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:39:43 UTC

Locations

FR(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Study Arms (3)

slight periodontal disease

moderate periodontal disease

severe periodontal disease

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations