NCT01949064

Brief Summary

The treatment of craniomandibular disorders is a challenging task. Many different treatments are yet available with occlusal splints being one of the most commonly used. A relative new diagnostic and treatment alternative is the Grindcare device. This enables the electromyographic (EMG) assessment of the activity of the temporal muscle and the contigent electrical stimulation of this muscle as bio-feedback whenever the EMG activity exceeds a certain limit. This stimulation results to a sudden break of the muscle activity. Aim of this study is to compare the therapeutic efficacy of the Grindcare device in pain reduction at female non-chronic CMD patients to that of a Michigan-type splint. Our null-hypothesis was that there is no difference between the device and the splint in the reduction of pain intensity.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
44

participants targeted

Target at P25-P50 for phase_2

Timeline
Completed

Started Jul 2011

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2011

Completed
2.2 years until next milestone

First Submitted

Initial submission to the registry

September 17, 2013

Completed
7 days until next milestone

First Posted

Study publicly available on registry

September 24, 2013

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2014

Completed
Last Updated

December 3, 2014

Status Verified

December 1, 2014

Enrollment Period

2.5 years

First QC Date

September 17, 2013

Last Update Submit

December 2, 2014

Conditions

Outcome Measures

Primary Outcomes (1)

  • Worst perceived pain

    1 week

Study Arms (2)

Michigan-type occlusal splint

ACTIVE COMPARATOR

Occlusal splint, Michigan-type

Device: Michigan-type occlusal splint

Grindcare

ACTIVE COMPARATOR

Biofeedback device

Device: Grindcare

Interventions

GrindcareDEVICE
Grindcare
Michigan-type occlusal splint

Eligibility Criteria

Age18 Years - 70 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Signed informed consent form
  • Age between 18 and 70 years
  • Non-chronic painful CMD with/without mandibular movement restriction
  • Female

You may not qualify if:

  • Pregnancy or breastfeeding
  • Chronic Pain Status higher than 2
  • Known allergic reaction against the gel pads
  • Electronic implants (pacemaker, defibrilator, insulin pump)
  • Facial pain of dental or neuropathic etiology
  • Traumatic injuries of the face / operations
  • Dental treatment need
  • Problems with swallowing reflex

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Poliklinik für Zahnärztliche Prothetik

Heidelberg, 69120, Germany

Location

MeSH Terms

Conditions

Facial Pain

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Nikolaos Nikitas Giannakopoulos, Dr.med.dent,M.Sc

    Poliklinik für Zahnärztliche Prothetik

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr.med.dent., M.Sc.

Study Record Dates

First Submitted

September 17, 2013

First Posted

September 24, 2013

Study Start

July 1, 2011

Primary Completion

January 1, 2014

Study Completion

January 1, 2014

Last Updated

December 3, 2014

Record last verified: 2014-12

Locations