Is There a Correlation Between the Pulmonary Artery Pressure and the Acceleration of the Flow in the Pulmonary Artery Evaluated by Transesophageal Echocardiography (TOE) ?

NCT01947257 | Unknown

• 2 other identifiers: 2013-A00730-452013-19
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

The measure of the pulmonary artery pressure (PAP) is a very useful index in intensive care to estimate right ventricular after load. The reference technique for this measure is the right catheterism which is an invasive technique. It is possible to estimate the pulmonary artery pressure by using transthoracic echocardiography (TTE) which allows, using the continuous Doppler, the measure of maximum speed of tricuspid regurgitation (TRvmax). The measure of the TRvmax can however be difficult for intensive care patients with little echogenicity or impossible for those having no tricuspid leak. The evaluation of the tricuspid regurgitation is also particularly difficult using TOE. To avoid these drawbacks, one can use the analysis of the pulmonary ejection in the pulmonary artery (PAAT) with TOE. However, the data of the literature are controversial on this method and it was not validated in mechanically ventilated intensive care patients. The aim of this work is to compare three methods of measure of the PAP: the measure TRVMAX (by means of the tricuspid leak) by transthoracic echocardiography, the measure of the TAAP by transesophageal ultrasound and the direct measure of the pulmonary pressures by right catheterization, in ventilated patients already monitored with a catheter in the right cavities for usual indications in intensive care (ARDS, shock). We shall analyze then the correlation between the TRVmax, the TAAP and the pressures measured by the right catheterism which serves as reference technique.

Conditions

Ventilated Patients

Outcome Measures

Primary Outcomes (1)

• measure of the pulmonary artery pressure

  12 months

Study Arms (1)

ventilated patients

OTHER

Other: the measure TRVMAX; Other: the measure of the pulmonary artery; Other: the direct measure of the pulmonary pressures

Interventions

the measure TRVMAX OTHER

by transthoracic echocardiography

ventilated patients

the measure of the pulmonary artery OTHER

by transesophageal ultrasound

ventilated patients

the direct measure of the pulmonary pressures OTHER

by right catheterization

ventilated patients

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients aged over 18 years
• Admitted to intensive care
• Mechanically ventilated and sedated
• Carrying a right catheterization
• Making a ETO indicated by the medical team or doctor in charge of the patient

You may not qualify if:

• Patients under 18 years
• expectant mother
• Patients without health insurance
• Refusal to close

Sponsors & Collaborators

• Assistance Publique Hopitaux De Marseille: lead

Study Sites (1)

Assistance Publique Hopitaux de Marseille

Marseille, 13354, France

Location

Study Officials

• LOIC MONDOLONI

  Assistance Publique Hopitaux De Marseille

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 31, 2013
• First Posted: September 20, 2013
• Study Start: September 1, 2013
• Primary Completion: July 1, 2014
• Study Completion: January 1, 2015
• Last Updated: September 1, 2014

Record last verified: 2014-08

Locations

FR (1)