Trials Sponsors Conditions Drugs Pricing

Conditions

Esophagogastric Junction Outflow Obstruction

Keywords

esophagogastric junction outflow obstructionEGOOPer oral endoscopic myotomyPOEMGastroesophageal reflux diseaseGERD

Outcome Measures

Primary Outcomes (1)

Change in dysphagia severity
Dysphagia will be measured by Dysphagia score and Eckhardt score at 2 and 6 months after the procedure (The Eckhardt score takes into consideration symptoms of dysphagia, chest pain, regurgitation and chest pain)
2 and 6 months

Secondary Outcomes (7)

Resolution in Esophago-gastric junction (EGJ) outflow obstruction by HRM performed 2 months after the procedure
2 months
Change in participants' quality of life
2 and 6 months
Complication rate
2 years
Length of hospital stay
2 years
Procedural times
2 years
+2 more secondary outcomes

Study Arms (1)

EGOO

EXPERIMENTAL

Patients presenting with symptomatic gastroesophageal junction outflow obstruction (EGOO)who will be treated with Per oral endoscopic myotomy (POEM)

Procedure: POEM

Interventions

POEMProcedure

Patients will receive Per oral endoscopic myotomy (POEM) for symptomatic gastroesophageal junction outflow obstruction (EGOO)

EGOO

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years - 70 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Consecutive adult patients (18-70 years of age) with symptomatic dysphagia (dysphagia score ≥2) EGOO that is diagnosed by high resolution manometry.
Ability to give informed consent.

You may not qualify if:

Sponsors & Collaborators

Johns Hopkins University
Otherlead

Study Sites (1)

Johns Hopkins Hospital

Baltimore, Maryland, 21287, United States

MeSH Terms

Conditions

Gastroesophageal Reflux

Condition Hierarchy (Ancestors)

Esophageal Motility DisordersDeglutition DisordersEsophageal DiseasesGastrointestinal DiseasesDigestive System Diseases

Study Officials

Mouen A Khashab, MD
Johns Hopkins University
PRINCIPAL INVESTIGATOR

Enrollment

15 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NA
Masking: NONE
Purpose: TREATMENT
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

September 5, 2013

First Posted

September 13, 2013

Study Start

May 2015

Date type not reported

This date has not been verified as actual or estimated.

Per Oral Endoscopic Myotomy (POEM) for Esophagogastric Junction Outflow Obstruction (EGOO)

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (7)

Study Arms (1)

EGOO

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (7)

Study Arms (1)

EGOO

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Source record

Locations