NCT01928706

Brief Summary

Purpose: the aim of the present study was to analyze the impact of mandibular denture relining with soft or hard denture liners in the oral health related quality of life (OHRQoL) of edentulous patients. The null hypothesis was that there would be no difference in OHRQoL findings after mandibular denture relining between patient groups treated with hard or soft denture liners.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
44

participants targeted

Target at P25-P50 for not_applicable quality-of-life

Timeline
Completed

Started Mar 2009

Longer than P75 for not_applicable quality-of-life

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2009

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2012

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2012

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

August 6, 2013

Completed
21 days until next milestone

First Posted

Study publicly available on registry

August 27, 2013

Completed
Last Updated

August 27, 2013

Status Verified

August 1, 2013

Enrollment Period

2.9 years

First QC Date

August 6, 2013

Last Update Submit

August 21, 2013

Conditions

Keywords

edentulismdenture linerprosthodonticsOHIP EDENT

Outcome Measures

Primary Outcomes (1)

  • Change from Baseline in Oral health related quality of life at 90 days after denture relining

    The Oral Health Related Quality of Life (OHRQoL) was assessed through the application of the questionnaire OHIP EDENT at baseline and 90 days post denture relining. Four domains developed for the Brazilian OHIP-EDENT9 were used: (D1) 'masticatory-related complaints, (D2) 'psychological discomfort and disability', (D3) 'social disability' and (D4) 'oral pain and discomfort'. The questionnaires were carried out via interviews by one individual examiner , who was blinded for the denture liner. The interviews lasted approximately ten minutes.Three possible answers to questions one to nineteen with their scores in parenthesis were given as options: never (0), sometimes (1) or almost always (2).

    The oral health related quality of life was evaluated before relining (T0- baseline), and after 90 days post denture relining.

Study Arms (2)

Denture liner Mucopren Soft; Group 1

EXPERIMENTAL

The existing mandibular dentures were relined with a soft silicone-based denture liner (Mucopren Soft; Group 1; n=22).

Other: Denture liner Mucopren Soft; Group 1

Denture liner Kooliner; Group 2

ACTIVE COMPARATOR

The existing mandibular dentures were relined with a a hard acrylic resin based denture liner (Kooliner; Group 2 n=22).

Other: Denture liner Kooliner; Group 2

Interventions

Complete denture wearers had their existing mandibular dentures relined with a soft silicone-based denture liner (Mucopren Soft; Group 1; n=22)

Also known as: Mucopren Soft relining
Denture liner Mucopren Soft; Group 1

Complete denture wearers had their existing mandibular dentures relined with a hard acrylic resin based denture liner (Kooliner; Group 2;n=22) with chairside procedures.

Also known as: Kooliner
Denture liner Kooliner; Group 2

Eligibility Criteria

Age40 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Edentulous in both jaws
  • Complete denture wearers
  • Clinically acceptable occlusal relationships
  • Healthy mucosa, i.e. with no signs of inflammation, traumatic lesions, candidiasis or hyperplasia.

You may not qualify if:

  • Residual vertical bone height of 10 mm or less
  • No attached mucosa in any region of mandible (type E)
  • Dentures with deteriorated intaglio surfaces
  • Dentures with large pre-existing fractures
  • Dentures with severely altered occlusal vertical dimension
  • Extremely worn artificial teeth
  • Dentures with unsatisfactory occlusions
  • Neurological diseases
  • Lack of motor coordination
  • Difficulty of understanding instructions and the conditions of the study
  • Patients with residual roots, cysts or bone spicules
  • Patients with allergies to methyl methacrylate or silicone
  • Knife-edge mandibular ridges.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ribeirao Preto Dental School University of Sao Paulo

Ribeirão Preto, São Paulo, 14.040-904, Brazil

Location

MeSH Terms

Interventions

kooliner

Study Officials

  • C H Lovato, pHD

    Ribeirao Preto Dental School University of Sao Paulo

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dds, MsC, PhD

Study Record Dates

First Submitted

August 6, 2013

First Posted

August 27, 2013

Study Start

March 1, 2009

Primary Completion

February 1, 2012

Study Completion

May 1, 2012

Last Updated

August 27, 2013

Record last verified: 2013-08

Locations