NCT01920776

Brief Summary

The investigators hypothesize that lung ultrasound and echocardiography will benefit the septic shock patients by making the treatment more precisely and rapidly. Septic shock patients from multicenter will be enrolled in the study. They will be randomly divided into two groups. The routine treatment group will receive routine treatment according to the SSC guideline. The study group will receive additional ultrasound examination, which will decide the improvement of therapy. Therapy change based on ultrasound results and the prognosis will be recorded.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2013

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

August 1, 2013

Completed
11 days until next milestone

First Posted

Study publicly available on registry

August 12, 2013

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2014

Completed
Last Updated

August 12, 2013

Status Verified

August 1, 2013

Enrollment Period

1 year

First QC Date

August 1, 2013

Last Update Submit

August 9, 2013

Conditions

Septic Shock

Keywords

critical ultrasound

Outcome Measures

Primary Outcomes (1)

  • mortality

    28day

Study Arms (1)

Rutine treatment group, Ultrasound group

EXPERIMENTAL
Other: ultrasound examinationOther: Ultrasound group

Interventions

ultrasound examinationOTHER
Rutine treatment group, Ultrasound group
Ultrasound groupOTHER

Ultrasound group will receive ultrasound examination at least once a day, the results will be noted to the attending who is in charge of the treatment.

Rutine treatment group, Ultrasound group

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • age\>18yr
  • survive more than 24hrs
  • fulfilled septic shock

You may not qualify if:

  • age \< 18yr
  • pregnant
  • DNR

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Peking Union Medical College Hospital ICU

Beijing, 100730, China

RECRUITING

Related Publications (1)

  • Du W, Wang XT, Long Y, Liu DW. Efficacy and Safety of Esmolol in Treatment of Patients with Septic Shock. Chin Med J (Engl). 2016 Jul 20;129(14):1658-65. doi: 10.4103/0366-6999.185856.

    PMID: 27411452DERIVED

MeSH Terms

Conditions

Shock, Septic

Condition Hierarchy (Ancestors)

SepsisInfectionsSystemic Inflammatory Response SyndromeInflammationPathologic ProcessesPathological Conditions, Signs and SymptomsShock

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr

Study Record Dates

First Submitted

August 1, 2013

First Posted

August 12, 2013

Study Start

July 1, 2013

Primary Completion

July 1, 2014

Last Updated

August 12, 2013

Record last verified: 2013-08

Locations

CN(1)