Body Composition in Preschool Children

NCT01920724 | Completed

• 2 other identifiers: MU-IRB 2010/211.0807A09/2554
• Study Type: observational
• Target: 137
• Locations: 1 country
• Sites: 1

Brief Summary

Thailand has been facing with the double burden of malnutrition. Many studies in Thailand, which aim to explore the situation, causes, and strategies to prevent obesity, have focused on adults, adolescents, or school-aged children. Few studies have been conducted in preschool children. Obesity or stunting during childhood increases the risk of being obesity in adulthood and leads to chronic diseases. If obesity is established in adulthood, it is difficult to reduce the excess weight. Thus, the prevention of obesity or stunting in young children should be highly considered. Study of dietary pattern and reliable field methods to measure fat mass (FM) in children may partly contribute to primary prevention of childhood obesity. The deuterium dilution technique is an accurate and suitable method for children and population-based studies. However, it has not been widely used in children in Thailand. Hence, this study aimed to utilize the deuterium dilution technique for assessing body composition and to determine the quality and quantity of dietary intake among children 3-5 years of age with different nutritional status. We conducted a cross-sectional study in 15 daycare centers in Nakhon Pathom and Samut Prakarn provinces. 120 preschoolers were purposively selected according to their nutritional status: stunted, thin, normal, and overweight/obese. Anthropometric measurements were conducted. Body composition was determined based on total body water using deuterium dilution technique. Dietary intake data were obtained using 2-day 24 hr recall.We hypothesized that stunted and obese children will have more fat mass compared to the normal children.

Conditions

Obesity; Wasting

Keywords

Preschool children; Body composition

Outcome Measures

Primary Outcomes (1)

• Body composition

  Body fatness

  4 months

Secondary Outcomes (1)

• Nutrient intake

  4 months

Study Arms (1)

wasting, obesity, stunting, normal

wasting (BMI for age Z-scores \< -2 SD), normal (-1 SD ≤ BMI for age Z-scores ≤ +1 SD), obesity (BMI for age Z-scores \> +2 SD), and stunting (HAZ \< -2 SD).

Eligibility Criteria

• Age: 3 Years - 5 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Children in the daycare centers in Nakhon Pathom and Samut Prakarn porvinces will be screened and categorized into 4 groups, including wasting (BMI for age Z-scores \< -2 SD), normal (-1 SD ≤ BMI for age Z-scores ≤ +1 SD), obesity (BMI for age Z-scores \> +2 SD), and stunting (HAZ \< -2 SD). Then, they will be randomly selected to participate in this study.

You may qualify if:

• Healthy children
• Aged 3-5 years
• BMI or HAZ fall in the study protocol

You may not qualify if:

• Chronic diseases
• Ongoing medical treatments likely to affect body composition
• Malformation or muscle diseases

Sponsors & Collaborators

• Mahidol University: lead
• International Atomic Energy Agency: collaborator

Study Sites (1)

Institute of Nutrition, Mahidol University

Salaya, Changwat Nakhon Pathom, 73170, Thailand

Location

Related Links

• Introduction to body composition assessment

Biospecimen

Retention: SAMPLES WITHOUT DNA

Urine samples

MeSH Terms

Conditions

Obesity; Cachexia

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Weight Loss; Body Weight Changes; Thinness

Study Officials

• Tippawan Pongcharoen, Ph.D.

  Mahidol University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 13, 2013
• First Posted: August 12, 2013
• Study Start: November 1, 2010
• Primary Completion: July 1, 2012
• Study Completion: July 1, 2012
• Last Updated: February 3, 2023

Record last verified: 2023-02

Data Sharing

• IPD Sharing: Will not share

Locations

TH (1)