Anti-Mullerian Hormone Changes After Laparoscopic Ovarian Cystectomy for Endometrioma Compared With the Non-ovarian Conditions

NCT01919333 | Unknown

• 1 other identifier: MTU-OB-3-096/56
• Study Type: observational
• Target: 56
• Locations: 1 country
• Sites: 1

Brief Summary

This aim of the study is to evaluate the impact of endometrioma and laparoscopic cystectomy on ovarian reserve as measured by serum antimullerian hormone and to study the different effects of levels of serum antimullerian hormone between laparoscopic cystectomy and the non-ovarian pelvic surgery.

Conditions

Ovarian Reserve

Outcome Measures

Primary Outcomes (1)

• Serum AMH levels

  6 months

Study Arms (2)

laparoscopic ovarian cystectomy

the group who laparoscopic ovarian cystectomy are performed for endometrioma

laparoscopic non- ovarian pelvic surgery

the group whom laparoscopic non- ovarian pelvic surgery are performed

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Reproductive women , age 18- 45 years who undergo laparoscopic ovarian cystectomy or laparoscopic non- ovarian pelvic surgery

You may qualify if:

• Participants must be between the ages of 18 - 45 during enter the study .
• Every participants have to completely understand the process of this study and have written informed consent .
• Having regular menstrual cycles (21-35 days) at the time of operation
• no evidence of any other endocrine disorders such as diabetes mellitus, thyroid dysfunction, hyperprolactinemia, congenital adrenal hyperplasia, Cushing's syndrome, or adrenal insufficiency.
• undergo laparoscopic ovarian cystectomy or laparoscopic non- ovarian pelvic surgery for benign pelvic disease
• No previous history of adnexal surgery
• No any suspicious findings of malignant ovarian diseases
• Never taking any medication such as oral pill and hormonal drugs within 3 months before the enrollment.
• pathological diagnosis of excised ovarian tissue confirm as endometriotic cyst in study group and other benign pelvic disease in control group

You may not qualify if:

• polycystic ovarian syndrome according to the Rotterdam criteria
• pathological report as the malignant diseases
• have operation conversion to open-laparotomy

Sponsors & Collaborators

• Thammasat University: lead

Study Sites (1)

Faculty of medicine , Thammasat university

Rangsit City Municipality, Pathumthanee, 12120, Thailand

RECRUITING

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: August 6, 2013
• First Posted: August 9, 2013
• Study Start: December 1, 2012
• Primary Completion: December 1, 2013
• Last Updated: August 9, 2013

Record last verified: 2013-08

Locations

TH (1)