NCT01918891

Brief Summary

The Stroke CTI study is a 3 arm randomized, controlled trial designed to assess the effectiveness of a nurse practitioner (NP) only and a NP and health coach (HC) community transitions intervention (CTI) in reducing secondary stroke risk by helping patients lower their systolic blood pressure.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
495

participants targeted

Target at P75+ for not_applicable hypertension

Timeline
Completed

Started Sep 2012

Longer than P75 for not_applicable hypertension

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2012

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

August 5, 2013

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 8, 2013

Completed
4.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2018

Completed
Last Updated

October 1, 2019

Status Verified

September 1, 2019

Enrollment Period

5.8 years

First QC Date

August 5, 2013

Last Update Submit

September 30, 2019

Conditions

Keywords

stroketransient ischemic attackHigh blood pressureHypertension

Outcome Measures

Primary Outcomes (1)

  • Reduction of systolic blood pressure

    Patients randomized to the NP only and the NP+HC transitional care interventions will have greater 3 and 12 month reduction in SBP than patients in Usual Home Care.

    Baseline to 3 and 12 months.

Secondary Outcomes (2)

  • Cost-effectiveness of NP-only and NP+HC relative to UHC

    VNSNY home care admission to 3 and 12 months post admission

  • Influence on post-stroke patients' function and health-related quality of life (QoL)

    Baseline to 3 and 12 months

Other Outcomes (1)

  • Moderators and mediators that may affect treatment outcomes

    Baseline to 3 and 12 months

Study Arms (3)

Usual Home Care

NO INTERVENTION

Regardless of study arm, all patients will receive usual home health services: a physician-ordered plan of care; skilled nursing and/or therapy services as prescribed by the MD; patient education, monitoring and hands-on care; and home health aide services depending on functional deficits and availability of unpaid caregivers.

Nurse Practitioner + Health Coach

EXPERIMENTAL

The NP + HC arm will include the same protocol as the NP only arm plus 30 additional days of support. The HC will pick up the case after the initial 30 days and follow up with the plan of care jointly established by the patient, NP and HC. The focus will be on ongoing self-management coaching, providing preparation support for physician visits, and linking patient to additional community resources, as needed.

Behavioral: Nurse Practitioner OnlyBehavioral: Nurse Practitioner + Health Coach

Nurse Practitioner Only

EXPERIMENTAL

The NP only program will provide a 30 day intervention via in-home and telephone encounters for patients randomized to this group. In the first 30 days post-enrollment the NP will focus on medical case management and coordination with primary care providers and specialists, provide self-management coaching, and intervene if gaps in care are identified - all with a focus on BP reduction and preparing the patient for ongoing BP maintenance.

Behavioral: Nurse Practitioner Only

Interventions

Nurse Practitioner + Health CoachNurse Practitioner Only
Nurse Practitioner + Health Coach

Eligibility Criteria

Age21 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Newly admitted to the VNSNY post acute care program
  • years of age or older
  • Black and/or Hispanic
  • Speaks English or Spanish
  • History of stroke or transient ischemic attack (TIA)
  • Hypertension diagnosis
  • Average screening systolic BP \>= 140 mmHg
  • Is available to participate in intervention activities during the study timeframe if randomized to treatment group

You may not qualify if:

  • Dialysis
  • End stage renal disease
  • Kidney transplant
  • Severe heart failure
  • Significant cognitive impairment. Unable to provide informed consent, accurate self-report, and/or unable to participate effectively in intervention
  • Significant verbal speech impairment. Unable to participate in intervention telephone sessions
  • Patients with upper arm circumference outside of valid use parameters for the automated device used for eligibility screening

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Visiting Nurse Service of New York

New York, New York, 10001, United States

Location

Related Publications (3)

  • Osakwe ZT, Barron Y, McDonald MV, Feldman PH. Effect of Nurse Practitioner Interventions on Hospitalizations in the Community Transitions Intervention Trial. Nurs Res. 2021 Jul-Aug 01;70(4):266-272. doi: 10.1097/NNR.0000000000000508.

  • Feldman PH, McDonald MV, Trachtenberg M, Trifilio M, Onorato N, Sridharan S, Silver S, Eimicke J, Teresi J. Reducing Hypertension in a Poststroke Black and Hispanic Home Care Population: Results of a Pragmatic Randomized Controlled Trial. Am J Hypertens. 2020 Apr 1;33(4):362-370. doi: 10.1093/ajh/hpz148.

  • Feldman PH, McDonald MV, Trachtenberg MA, Schoenthaler A, Coyne N, Teresi J. Center for stroke disparities solutions community- based care transition interventions: study protocol of a randomized controlled trial. Trials. 2015 Jan 27;16:32. doi: 10.1186/s13063-015-0550-3.

Related Links

MeSH Terms

Conditions

HypertensionStrokeIschemic Attack, Transient

Interventions

Nurse Practitioners

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular DiseasesCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesBrain Ischemia

Intervention Hierarchy (Ancestors)

NursesHealth PersonnelHealth Care Facilities Workforce and Services

Study Officials

  • Penny H Feldman, PhD

    Visiting Nurse Service of New York

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 5, 2013

First Posted

August 8, 2013

Study Start

September 1, 2012

Primary Completion

June 1, 2018

Study Completion

June 1, 2018

Last Updated

October 1, 2019

Record last verified: 2019-09

Locations