NCT01915875

Brief Summary

The purpose of this study is to evaluate the impact of the global approach to the pain in cystic fibrosis patients with chronic or intermittent pain. The patients will receive in addition to an usual pharmacological and psychological management, sophrology sessions at home. The results of this study will provide a new strategy of management of the patient's pain.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
13

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2012

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 15, 2012

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

July 20, 2012

Completed
1 year until next milestone

First Posted

Study publicly available on registry

August 5, 2013

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 19, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 19, 2014

Completed
Last Updated

November 20, 2025

Status Verified

October 1, 2025

Enrollment Period

2.8 years

First QC Date

July 20, 2012

Last Update Submit

November 17, 2025

Conditions

Keywords

Cystic fibrosis-pain-sophrology

Outcome Measures

Primary Outcomes (1)

  • Change of maximum VAS

    Change of maximum VAS for the site presenting a max VAS in the month following the inclusion.

    6 months

Secondary Outcomes (7)

  • number of paroxystic episodes

    6 months

  • intensity of maximum VAS of the painful episodes

    6 months

  • Improvement of the quality of life

    6 months

  • BMI

    6 months

  • VEMS

    6 months

  • +2 more secondary outcomes

Study Arms (1)

sophrology sessions

EXPERIMENTAL

The sophrology is a dynamic method of physical and psychical relaxation

Other: sophrology sessions at home

Interventions

The sophrology is a dynamic method of physical and psychical relaxation

sophrology sessions

Eligibility Criteria

Age10 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Cystic fibrosis patients defined by a test sweat and / or 2 pathogenic mutations
  • Patients over 10 years
  • Patients with pain symptoms (VAS\> 4) recurrent (\> 4 episodes / month) or permanent since more than 6 months
  • Agreement of patients, and parents (for children) for sophrology sessions conducted at home.
  • Patient affiliated to social security

You may not qualify if:

  • Transplant patients or placed on a waiting list transplantation
  • Patients had a patient-support by techniques hypnosis or relaxation therapy, during or within 3 months.
  • Patients enrolled in another research interventional protocol.
  • Women without contraception or pregnant.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

hôpital Necker Enfants malades

Paris, 75015, France

Location

MeSH Terms

Conditions

Cystic Fibrosis

Condition Hierarchy (Ancestors)

Pancreatic DiseasesDigestive System DiseasesLung DiseasesRespiratory Tract DiseasesGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesInfant, Newborn, Diseases

Study Officials

  • Isabelle Sermet, MD, PhD

    Assistance Publique - Hôpitaux de Paris

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 20, 2012

First Posted

August 5, 2013

Study Start

February 15, 2012

Primary Completion

November 19, 2014

Study Completion

November 19, 2014

Last Updated

November 20, 2025

Record last verified: 2025-10

Locations