NCT01901640

Brief Summary

Phase : Phase III Indication : Erectile Dysfunction Study Design : open-label, fixed dose, 6-month extension study (parent study : DA8159\_EDD\_III)

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
302

participants targeted

Target at P50-P75 for phase_3

Timeline
Completed

Started Nov 2011

Shorter than P25 for phase_3

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2011

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2012

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

January 22, 2013

Completed
6 months until next milestone

First Posted

Study publicly available on registry

July 17, 2013

Completed
Last Updated

July 17, 2013

Status Verified

January 1, 2013

Enrollment Period

1 year

First QC Date

January 22, 2013

Last Update Submit

July 15, 2013

Conditions

Outcome Measures

Primary Outcomes (1)

  • Safety

    Safety evaluation included adverse events, standard 12-lead electrocardiograms and clinical laboratory measures. The AEs measured as percentage and number of patients.

    48 weeks(after 24 weeks of parent study), 52weeks(after 28weeks of parent study)

Secondary Outcomes (1)

  • International Index of Erectile Function(IIEF), GAQ(Global Assessment Questions), Shift to normal

    48 weeks(after 24 weeks of parent study), 52weeks(after 28weeks of parent study)

Study Arms (1)

DA-8159

EXPERIMENTAL

Udenafil(The study had one arm.)

Drug: DA-8159 (Udenafil)

Interventions

Eligibility Criteria

Age20 Years+
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Male patients aged 20 years or more diagnosed with erectile dysfunction(ED)

You may not qualify if:

  • Had uncontrolled blood pressure
  • Had hepatic or renal dysfunction
  • Had significant psychiatric disorders or drug abuses
  • Was currently under anticancer chemotherapy
  • Had a treatments for ED using other phosphodiesterase type 5(PDE-5) inhibitors

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Erectile Dysfunction

Interventions

udenafil

Condition Hierarchy (Ancestors)

Genital Diseases, MaleGenital DiseasesUrogenital DiseasesSexual Dysfunction, PhysiologicalMale Urogenital DiseasesSexual Dysfunctions, PsychologicalMental Disorders

Study Officials

  • S W Kim, MD, PhD

    the Catholic University of Korea St. Mary's Hospital

    PRINCIPAL INVESTIGATOR
  • D G Moon, MD, PhD

    Korea University Guro Hospital

    PRINCIPAL INVESTIGATOR
  • J J Kim, MD, PhD

    Korea University Anam Hospital

    PRINCIPAL INVESTIGATOR
  • N C Park, MD, PhD

    Pusan National University Hospital

    PRINCIPAL INVESTIGATOR
  • S W Lee, MD, PhD

    Samsung Medical Center

    PRINCIPAL INVESTIGATOR
  • J S Paick, MD, PhD

    Seoul National University Hospital

    PRINCIPAL INVESTIGATOR
  • T Y Ahn, MD, PhD

    Asan Medical Center

    PRINCIPAL INVESTIGATOR
  • K H Moon, MD, PhD

    Yeungnam University Hospital

    PRINCIPAL INVESTIGATOR
  • W S Chung, MD, PhD

    Ewha Womans University Hospital

    PRINCIPAL INVESTIGATOR
  • K S Min, MD, PhD

    Inje University

    PRINCIPAL INVESTIGATOR
  • J K Park, MD, PhD

    Chonbuk National University Hospital

    PRINCIPAL INVESTIGATOR
  • D Y Yang, MD, PhD

    Kangdong Sacred Heart Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 22, 2013

First Posted

July 17, 2013

Study Start

November 1, 2011

Primary Completion

November 1, 2012

Study Completion

November 1, 2012

Last Updated

July 17, 2013

Record last verified: 2013-01