NCT01899924

Brief Summary

The main objective of this study is to describe differential cognitive processing of various stimuli by a population of control subjects and a population of patients with selective cognitive deficits or altered states of consciousness by using dedicated ERP paradigms and high-density EEG picked up system.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
320

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jul 2013

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 27, 2013

Completed
4 days until next milestone

Study Start

First participant enrolled

July 1, 2013

Completed
15 days until next milestone

First Posted

Study publicly available on registry

July 16, 2013

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2017

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2018

Completed
Last Updated

March 10, 2015

Status Verified

March 1, 2015

Enrollment Period

4 years

First QC Date

June 27, 2013

Last Update Submit

March 8, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Cognitive processing assessment

    Specific Event Related Potential (ERP) presence. ERP measurements indicate if a patient or control subject has or has not performed the task we asked him to even if the subject performs the task covertly

    Day1

Secondary Outcomes (2)

  • Scalp topographies of ERPs

    Day 1

  • Cognitive assessment by means of specialized scales

    Day1, Day 356

Study Arms (1)

Event Related Potentials

EXPERIMENTAL
Behavioral: Event Related Potentials recording

Interventions

Event Related Potentials

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • adults between 18 and 80,
  • written informed consent obtained from the subject,
  • covers by social insurance,
  • absence of psychoactive drug intake in the week preceding the examination or alcohol intake the day before the exam

You may not qualify if:

  • pregnant patients or breastfeeding,
  • sensory deficit incompatible with the participation in tne study,
  • person under a legal protection measure, under guardianship,
  • psychoactive drug intake in the week preceding the examination or alcohol intake the day before the exam
  • Patients :
  • adults between 18 and 80,
  • written informed consent obtained from the patient or his relatives,
  • covers by social insurance,
  • patients with either focal or diffuse brain damage drom trauma, vascular, tumor or other aetiologies, or with a history of neonatal or congenital diseases,
  • patients with selective cognitive disorders or with altered states of consciousness
  • Pregnant patients or breastfeeding,
  • sensory deficit incompatible with the participation in the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU of Limoges

Limoges, 87042, France

RECRUITING

MeSH Terms

Conditions

Brain Injuries

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesCraniocerebral TraumaTrauma, Nervous SystemWounds and Injuries

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 27, 2013

First Posted

July 16, 2013

Study Start

July 1, 2013

Primary Completion

July 1, 2017

Study Completion

July 1, 2018

Last Updated

March 10, 2015

Record last verified: 2015-03

Locations