NCT01871155

Brief Summary

The purpose of this study is to determine whether a novel edible nutritious gel for patients with chewing and swallowing difficulties, Nutri-jelly, is effective in improving the quality of life of head and neck cancer patients while undergoing conventional radiotherapy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
64

participants targeted

Target at P50-P75 for not_applicable head-and-neck-cancer

Timeline
Completed

Started Jan 2012

Shorter than P25 for not_applicable head-and-neck-cancer

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2012

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2012

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

May 30, 2013

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 6, 2013

Completed
Last Updated

June 6, 2013

Status Verified

June 1, 2013

Enrollment Period

7 months

First QC Date

May 30, 2013

Last Update Submit

June 4, 2013

Conditions

Outcome Measures

Primary Outcomes (1)

  • Changes in Health-related quality of life score

    * Definitive cases: collect data at baseline (0-5), after Nutri-jelly (6-10), 11-15, 16-20, 21-25, 26-30, 31-35 fractions of RT), total period of 6 weeks * Palliative cases: collect data at baseline (0-5), after Nutri-jelly (6-10) fractions of RT, total period of 2 weeks

    0, 1, 2, 3, 4, 5, 6 weeks after radiotherapy

Study Arms (2)

Nutri-jelly along with radiotherapy

EXPERIMENTAL

Continuous intake: orally take 1-3 boxes / day for at least 3 days/ week during radiotherapy

Dietary Supplement: Nutri-jelly

Radiotherapy only

NO INTERVENTION

Receive either definitive (total of 30-35 fractions) or palliative ( total of 10 fractions) radiotherapy with no continuous intake of Nutri-Jelly

Interventions

Nutri-jellyDIETARY_SUPPLEMENT

an edible nutritious gel for chewing and swallowing difficulties 1 box contains 250 ml with 250 kcal 1 serving is considered as food supplement

Nutri-jelly along with radiotherapy

Eligibility Criteria

Age35 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • diagnosed as head and neck cancer
  • definitive or palliative radiotherapy treatment plan
  • can communicate well

You may not qualify if:

  • bleeding in the mouth
  • respiratory distress
  • psychiatric disorders
  • radiation field not involve masticatory and swallowing apparatus e.g. certain cases of laryngeal cancer and brain cancer

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mahavachiralongkorn cancer hospital

Pathum Thani, Changwat Pathum Thani, 12110, Thailand

Location

Related Links

MeSH Terms

Conditions

Head and Neck NeoplasmsDeglutition Disorders

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsEsophageal DiseasesGastrointestinal DiseasesDigestive System DiseasesPharyngeal DiseasesOtorhinolaryngologic Diseases

Study Officials

  • Dunyaporn Trachootham, DDS, PhD

    Faculty of Dentistry, Thammasat University, Thailand

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 30, 2013

First Posted

June 6, 2013

Study Start

January 1, 2012

Primary Completion

August 1, 2012

Study Completion

August 1, 2012

Last Updated

June 6, 2013

Record last verified: 2013-06

Locations